Non-coding RNAs in disease: from mechanisms to therapeutics

K Nemeth, R Bayraktar, M Ferracin… - Nature Reviews Genetics, 2024 - nature.com
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

microRNA dysregulation in neurodegenerative diseases: A systematic review

CA Juźwik, SS Drake, Y Zhang, N Paradis-Isler… - Progress in …, 2019 - Elsevier
While the root causes for individual neurodegenerative diseases are distinct, many shared
pathological features and mechanisms contribute to neurodegeneration across diseases …

[HTML][HTML] The role of microRNAs in neurodegenerative diseases: a review

S Li, Z Lei, T Sun - Cell Biology and Toxicology, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …

[HTML][HTML] Interplay between MicroRNAs and oxidative stress in neurodegenerative diseases

J Konovalova, D Gerasymchuk, I Parkkinen… - International journal of …, 2019 - mdpi.com
MicroRNAs are post-transcriptional regulators of gene expression, crucial for neuronal
differentiation, survival, and activity. Age-related dysregulation of microRNA biogenesis …

[HTML][HTML] microRNAs in Parkinson's disease: from pathogenesis to novel diagnostic and therapeutic approaches

L Leggio, S Vivarelli, F L'Episcopo, C Tirolo… - International journal of …, 2017 - mdpi.com
Parkinson's disease (PD) is the most prevalent central nervous system (CNS) movement
disorder and the second most common neurodegenerative disease overall. PD is …

Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair

B Marchetti, C Tirolo, F L'Episcopo, S Caniglia… - Aging cell, 2020 - Wiley Online Library
A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

[HTML][HTML] Recent advances in biomarkers for Parkinson's disease

R He, X Yan, J Guo, Q Xu, B Tang… - Frontiers in aging …, 2018 - frontiersin.org
Parkinson's disease (PD) is one of the common progressive neurodegenerative disorders
with several motor and non-motor symptoms. Most of the motor symptoms may appear at a …

Pharmacological regulation of endoplasmic reticulum structure and calcium dynamics: importance for neurodegenerative diseases

I Parkkinen, A Their, MY Asghar, S Sree… - Pharmacological …, 2023 - ASPET
The endoplasmic reticulum (ER) is the largest organelle of the cell, composed of a
continuous network of sheets and tubules, and is involved in protein, calcium (Ca2+), and …

miRNA in Parkinson's disease: From pathogenesis to theranostic approaches

A Elangovan, D Venkatesan, P Selvaraj… - Journal of Cellular …, 2023 - Wiley Online Library
Parkinson's disease (PD) is an age associated neurological disorder which is specified by
cardinal motor symptoms such as tremor, stiffness, bradykinesia, postural instability, and non …

[HTML][HTML] A review of molecular interplay between neurotrophins and miRNAs in neuropsychological disorders

S Abdolahi, A Zare-Chahoki, F Noorbakhsh… - Molecular …, 2022 - Springer
Various neurotrophins (NTs), including nerve growth factor, brain-derived neurotrophic
factor, neurotrophin-3, and neurotrophin-4, promote cellular differentiation, survival, and …