Recent advances in ocular lubrication

J Zhang, Y Su, J Wu, H Wang - Friction, 2024 - Springer
The ocular lubrication, where the eyelid constantly slides on the curved corneal surface, is
considered as one of primary lubrication systems in bio-tribology. Under reliable lubrication …

Reliability and efficacy of maximum fluorescein tear break-up time in diagnosing dry eye disease

Y Mou, H Xiang, L Lin, K Yuan, X Wang, Y Wu, J Min… - Scientific reports, 2021 - nature.com
This study aims to investigate the reliability and efficacy of maximum fluorescein tear break-
up time (FTBUTmax) in diagnosing dry eye disease (DED). 147 participants were enrolled in …

A model of tear-film breakup with continuous mucin concentration and viscosity profiles

M Dey, AS Vivek, HN Dixit, A Richhariya… - Journal of Fluid …, 2019 - cambridge.org
We propose an alternative to the prevailing framework for modelling tear-film breakup, which
posits a layered structure with a mucus layer next to the cornea and an aqueous layer on …

Tear-film breakup: The role of membrane-associated mucin polymers

A Choudhury, M Dey, HN Dixit, JJ Feng - Physical Review E, 2021 - APS
Mucin polymers in the tear film protect the corneal surface from pathogens and modulate the
tear-film flow characteristics. Recent studies have suggested a relationship between the loss …

Nonuniformities in miscible two-layer two-component thin liquid films

C Larsson, S Kumar - Physical Review Fluids, 2021 - APS
Depositing and obtaining a liquid film of uniform thickness is a problem integral to numerous
applications and requires an understanding of capillary leveling, Marangoni flows …

2D numerical simulation of tear film dynamics: Effects of shear-thinning properties

H Mehdaoui, HA Abderrahmane, FN Bouda… - European Journal of …, 2021 - Elsevier
The influence of the shear-thinning properties on tear dynamics is analyzed using 2D
numerical simulations. The simulations were conducted in conditions close to those of the …

Mathematical modelling of glob-driven tear film breakup

L Zhong, CF Ketelaar, RJ Braun… - … and biology: a …, 2019 - academic.oup.com
Evaporation is a recognized contributor to tear film thinning and tear breakup (TBU).
Recently, a different type of TBU is observed, where TBU happens under or around a thick …

On the Effect of Liquid Crystal Orientation in the Lipid Layer on Tear Film Thinning and Breakup

MJ Taranchuk, RJ Braun - arXiv preprint arXiv:2404.13225, 2024 - arxiv.org
The human tear film (TF) is thin multilayer fluid film that is critical for clear vision and ocular
surface health. Its dynamics are strongly affected by a floating lipid layer and, in health, that …

Duplex tear film evaporation analysis

MR Stapf, RJ Braun, PE King-Smith - Bulletin of Mathematical Biology, 2017 - Springer
Tear film thinning, hyperosmolarity, and breakup can cause irritation and damage to the
human eye, and these form an area of active investigation for dry eye syndrome research …

Dynamics of fluorescent imaging for rapid tear thinning

L Zhong, RJ Braun, CG Begley… - Bulletin of mathematical …, 2019 - Springer
A previous mathematical model has successfully simulated the rapid tear thinning caused by
glob (thicker lipid) in the lipid layer. It captured a fast spreading of polar lipid and a …