Molecular mechanisms of autophagy in cancer development, progression, and therapy

VAM Vitto, S Bianchin, AA Zolondick, G Pellielo… - Biomedicines, 2022 - mdpi.com
Autophagy is an evolutionarily conserved and tightly regulated process that plays an
important role in maintaining cellular homeostasis. It involves regulation of various genes …

[HTML][HTML] The regulatory role of autophagy-related miRNAs in lung cancer drug resistance

M Shahverdi, K Hajiasgharzadeh, AD Sorkhabi… - Biomedicine & …, 2022 - Elsevier
Autophagy is conserved cellular machinery that degrades un-usable proteins and cellular
components and has a crucial role in the pathogenesis and drug resistance of various …

Crosstalk between cGAS-STING pathway and autophagy in cancer immunity

Q Lu, Y Chen, J Li, F Zhu, Z Zheng - Frontiers in Immunology, 2023 - frontiersin.org
The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway is
critical in cancer immunity. Autophagy is a highly conserved process that is responsible for …

[HTML][HTML] LC3B: A microtubule-associated protein influences disease progression and prognosis

Y Chen, H Yi, S Liao, J He, Y Zhou, Y Lei - Cytokine & Growth Factor …, 2024 - Elsevier
Microtubule-associated protein 1 light chain 3B (MAP1LC3B, also known as LC3B) is a
mammalian homolog of the autophagy-related protein 8 (ATG8) family. It plays a crucial role …

Mechanistic investigation of the cytotoxicity of new Ce (IV) and Zn (II) complexes containing pyridinedicarboxylic acid derivatives against the SW480 cell line

A Aliabadi, S Abdolmaleki, S Khaksar - Journal of Molecular Structure, 2025 - Elsevier
Abstract Two cerium (IV)(C1) and zinc (II)(C2) complexes formulated as (aeea) 2 [Ce (pydc)
3]. 5H 2 O (where pydc is pyridine-2, 6-dicarboxylate and aeea is aminoethylethanolamine) …

Immunohistochemical expression of Beclin-1 and LC3B in benign and borderline ovarian tumors

WW Mousa, DM El-Guindy… - Tanta Medical …, 2024 - journals.lww.com
Background Epithelial ovarian tumors account for⁓ 90% of ovarian cancers. Recently
conducted studies have demonstrated autophagy role in tumor development and …

Immunohistochemical Expression of Beclin-1 in Gastric Carcinoma and Its Correlation with Her2 and Ki-67

ME Shabana, DM Abouelfadl, ASA Soliman… - Journal of Microscopy … - journals.lww.com
Objective: This study assesses the role of Beclin-1 expression in autophagy in gastric
carcinoma and its association with Her2 and Ki-67 expression. Materials and Methods: In …