Synthesis, in vitro inhibitor screening, structure–activity relationship, and molecular dynamic simulation studies of novel thioquinoline derivatives as potent α …
RD Forozan, MK Ghomi, A Iraji, MN Montazer… - Scientific Reports, 2023 - nature.com
New series of thioquinoline structures bearing phenylacetamide 9a–p were designed,
synthesized and the structure of all derivatives was confirmed using different spectroscopic …
synthesized and the structure of all derivatives was confirmed using different spectroscopic …
Synthesis, α-glucosidase inhibitory activity, and molecular dynamic simulation of 6-chloro-2-methoxyacridine linked to triazole derivatives
Α-glucosidase inhibition can be useful in the management of carbohydrate-related diseases,
especially type 2 diabetes mellitus. Therefore, in this study, a new series of 6-chloro-2 …
especially type 2 diabetes mellitus. Therefore, in this study, a new series of 6-chloro-2 …
Evaluation of novel 2-(quinoline-2-ylthio) acetamide derivatives linked to diphenyl-imidazole as α-glucosidase inhibitors: Insights from in silico, in vitro, and in vivo …
MK Ghomi, M Noori, M Mirahmad, A Iraji… - European Journal of …, 2024 - Elsevier
The inhibition of the α-glucosidase enzyme is crucial for targeting type 2 diabetes mellitus
(DM). This study introduces a series of synthetic analogs based on thiomethylacetamide …
(DM). This study introduces a series of synthetic analogs based on thiomethylacetamide …
Investigating the efficacy of naphthalene-thiazole hybrid hydrazones as α-glucosidase inhibitors
JY Al-Humaidi, AS Abouzied, MEA Zaki… - Journal of Molecular …, 2025 - Elsevier
In this study, a series of hydrazone derivatives containing naphthalene and thiazole hybrids
were synthesized through the condensation of (E)-4-methyl-2-(2-(naphthalen-1 …
were synthesized through the condensation of (E)-4-methyl-2-(2-(naphthalen-1 …
Synthesis, in vitro α-glucosidase inhibitory activities, and molecular dynamic simulations of novel 4-hydroxyquinolinone-hydrazones as potential antidiabetic agents
N Shayegan, S Haghipour, N Tanideh, A Moazzam… - Scientific Reports, 2023 - nature.com
In the present study, new structural variants of 4-hydroxyquinolinone-hydrazones were
designed and synthesized. The structure elucidation of the synthetic derivatives 6a–o was …
designed and synthesized. The structure elucidation of the synthetic derivatives 6a–o was …
Aryl-quinoline-4-carbonyl hydrazone bearing different 2-methoxyphenoxyacetamides as potent α-glucosidase inhibitors; molecular dynamics, kinetic and structure …
H Hamedifar, M Mirfattahi, M Khalili Ghomi… - Scientific Reports, 2024 - nature.com
Regarding the important role of α-glucosidase enzyme in the management of type 2
diabetes mellitus, the current study was established to design and synthesize aryl-quinoline …
diabetes mellitus, the current study was established to design and synthesize aryl-quinoline …
[PDF][PDF] RasaDokht Forozan, Minoo Khalili Ghomi 2, Aida Iraji 3, 4, Mohammad Nazari Montazer 2, Milad Noori 5, Navid Dastyafteh 5, Somayeh Mojtabavi 6 …
M Mahdavi - Scientific Reports, 2023 - academia.edu
New series of thioquinoline structures bearing phenylacetamide 9a–p were designed,
synthesized and the structure of all derivatives was confirmed using different spectroscopic …
synthesized and the structure of all derivatives was confirmed using different spectroscopic …
[PDF][PDF] Haleh Hamedifar, Mahroo Mirfattahi 3, Minoo Khalili Ghomi 3, Homa Azizian 4, Aida Iraji 5, 6, Milad Noori 7, Ali Moazzam 3, Navid Dastyafteh 7, Ali …
MH Hajimiri, M Mahdavi - Scientific Reports, 2024 - researchgate.net
Regarding the important role of α‑glucosidase enzyme in the management of type 2
diabetes mellitus, the current study was established to design and synthesize aryl‑quinoline …
diabetes mellitus, the current study was established to design and synthesize aryl‑quinoline …