Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

In vivo three-dimensional multispectral photoacoustic imaging of dual enzyme-driven cyclic cascade reaction for tumor catalytic therapy

S Lei, J Zhang, NT Blum, M Li, DY Zhang, W Yin… - Nature …, 2022 - nature.com
Non-invasive visualization of dynamic molecular events in real-time via molecular imaging
may enable the monitoring of cascade catalytic reactions in living systems, however effective …

Superstructural ordering in self-sorting coacervate-based protocell networks

W Mu, L Jia, M Zhou, J Wu, Y Lin, S Mann, Y Qiao - Nature Chemistry, 2024 - nature.com
Bottom-up assembly of higher-order cytomimetic systems capable of coordinated physical
behaviours, collective chemical signalling and spatially integrated processing is a key …

Synthetic cells: from simple bio‐inspired modules to sophisticated integrated systems

C Guindani, LC da Silva, S Cao, T Ivanov… - Angewandte …, 2022 - Wiley Online Library
Bottom‐up synthetic biology is the science of building systems that mimic the structure and
function of living cells from scratch. To do this, researchers combine tools from chemistry …

Nanoparticle-assembled bioadhesive coacervate coating with prolonged gastrointestinal retention for inflammatory bowel disease therapy

P Zhao, X Xia, X Xu, KKC Leung, A Rai, Y Deng… - Nature …, 2021 - nature.com
A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …

Targeted liposomal drug delivery: a nanoscience and biophysical perspective

Y Liu, KMC Bravo, J Liu - Nanoscale horizons, 2021 - pubs.rsc.org
Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …

A biomimetic aggregation‐induced emission photosensitizer with antigen‐presenting and hitchhiking function for lipid droplet targeted photodynamic immunotherapy

X Xu, G Deng, Z Sun, Y Luo, J Liu, X Yu… - Advanced …, 2021 - Wiley Online Library
Photodynamic therapy (PDT) is a promising alternative approach for effective cancer
treatment that is associated with an antitumor immune response. However …

Enzyme mimics for engineered biomimetic cascade nanoreactors: mechanism, applications, and prospects

X Zhang, G Li, G Chen, D Wu, Y Wu… - Advanced Functional …, 2021 - Wiley Online Library
Multiple enzyme‐driven biological catalytic cascades occur in living organisms, guiding
highly efficient and selective transformations of substrates. Inspired by the merits of these …

Giant coacervate vesicles as an integrated approach to cytomimetic modeling

Y Zhang, Y Chen, X Yang, X He, M Li… - Journal of the …, 2021 - ACS Publications
Although giant unilamellar vesicles (GUVs) have been extensively studied as synthetic cell-
like microcompartments, their applicability as cytomimetic models is severely compromised …