Backgrounds Poorly regulated mitosis and chromosomal instability are common
characteristics in malignant tumor cells. Kinesin family member 2 C (KIF2C), also known as …

Chromosome stability is ensured by precisely fine-tuned dynamics of mitotic spindles, which
are controlled by a network of various microtubule-associated and interacting proteins …

The biological function of proteins is heavily influenced by their structures and their
organization into assemblies such as protein complexes and regulatory networks. Mass …

We present a hydrogen/deuterium exchange workflow coupled to tandem mass
spectrometry (HX-MS2) that supports the acquisition of peptide fragment ions alongside their …

The Mass Spec Studio package was designed to support the extraction of hydrogen-
deuterium exchange and covalent labeling data for a range of mass spectrometry (MS) …

Abstract KIF2C/MCAK (KIF2C) is the most well-characterized member of the kinesin-13
family, which is critical in the regulation of microtubule (MT) dynamics during mitosis, as well …

Electron transport phosphorylation is the central mechanism for most prokaryotic species to
harvest energy released in the respiration of their substrates as ATP. Microorganisms have …

Hydrogen/deuterium exchange mass spectrometry (HX-MS) is a method used to study
solution-phase protein structure and dynamics. Despite its many applications, HX-MS is …

The functional state of proteins is inherently flexible, which allows them to interact with other
biomolecules, including other proteins, to carry out many of their cellular functions …

Towards Probing Structure and Function Relationships of Proteins in Complex Sample Types
Using HX-MS Page 1 University of Calgary PRISM Repository https://prism.ucalgary.ca The …