This review summarizes the current knowledge on lactones, a class of biologically active
natural products isolated from a wide range of living organisms. Butenolide, 5, 6 …

Marine sponges and tunicates, fungi, bacteria, and other lower animal forms are rich
sources of structurally unusual, biologically active peptides. 1, 2 These peptides exhibit a …

The vast majority of commodity materials are obtained from fossil fuels. However, many
studies predict that all fossil resources will be depleted within a few centuries. Biomass …

Containing fully authenticated data on virtually all known natural products, the" Dictionary of
Natural Products", main work, published in 1993 was the end result of over 12 years …

Marine organisms are the source of a great variety of biologically active secondary
metabolites. Many of these are heterocyclic and contain considerably modified amino acid …

A new room temperature polymerization method has been developed for the synthesis of
high molecular weight polyesters directly from carboxylic acids and phenols. The solution …

Covering: up to 2014 In this review we investigate the use of complex ester fragment
couplings within natural product total synthesis campaigns. We first outline the different …

Ever since the first isolation of Exaltolide 1 (Figure 1) in 1927 by Kerschbaum, 1 interest in
macrocyclic lactones, defined as lactones with more than 8 atoms in the ring, has been …

Macrocyclic scaffolds are commonly found in bioactive natural products and pharmaceutical
molecules. So far, a large number of macrocyclic natural products have been isolated and …

An overview is given of the recent trends in the synthesis of naturally occurring 8-and 9-
membered lactones. During the past three decades of synthetic studies of medium-sized …