Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …

Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Bioorthogonal chemistry provides a new avenue for disease treatment by generating
therapeutic agents in situ. However, two crucial issues have to be considered for future …

The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …

Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

Prodrugs are chemically modified drug molecules that are inactive before administration.
After administration, they are converted in situ to parent drugs and induce the mechanism of …

In recent years, lanthanide (Ln) porphyrinoids have received increasing attention as
theranostics. Broadly speaking, the term 'theranostics' refers to agents designed to allow …

Proteolysis targeting chimera (PROTAC) is an emerging protein degradation strategy, which
shows excellent advantages in targeting those so-called “undruggable” proteins. However …

As one of the typical bioorthogonal reactions, copper (I)-catalyzed azide-alkyne
cycloaddition (CuAAC) reaction holds great potential in organic synthesis, bioconjugation …

Photodynamic therapy (PDT) with selectivity and security has been widely acknowledged as
a promising therapeutic option for cancer treatment. With the swift blossom of phototherapy …