Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream
with Janus kinases (JAK) family protein and capable of integrating inputs from different …

Fenugreek (Trigonella foenum-graecum) is a legume and it has been used as a spice
throughout the world to enhance the sensory quality of foods. It is known for its medicinal …

Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic
transcription factors that mediate intracellular signaling that is usually generated at cell …

Plant‐derived natural products have long‐standing utility toward treating degenerative
diseases. It is estimated that about two‐thirds of world population depend on traditional …

Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

Background Chronic diseases are a major cause of mortality worldwide, and despite the
recent development in treatment modalities, synthetic drugs have continued to show toxic …

Diosgenin, a steroidal sapogenin, occurs abundantly in plants such as Dioscorea alata,
Smilax China, and Trigonella foenum graecum. This bioactive phytochemical not only is …

The signal transducer and activator of transcription (STAT) proteins have important roles in
biological processes. The abnormal activation of STAT signalling pathways is also …

Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

Novel and alternative options are being adopted to combat the initiation and progression of
human cancers. One of the approaches is the use of molecules isolated from traditional …