As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Patients with cancer have an increased risk for venous thrombosis. Interestingly, different
cancer types have different rates of thrombosis, with pancreatic cancer having one of the …

Increasing evidence shows that the anti-tumor functions of tumor-infiltrating T lymphocytes
(TILs) were inhibited significantly, but the underlying mechanisms remain not fully …

Lung injury may persist during the recovery period of COVID-19 as shown through imaging,
six-minute walk, and lung function tests. The pathophysiological mechanisms leading to …

Background Colon cancer is invariably accompanied by altered coagulation activity;
however, the precise role of phosphatidylserine (PS) in the hypercoagulable state of colon …

Small molecules targeting bromodomains of BET proteins possess strong anti-tumor
activities and have emerged as potential therapeutics for cancer. However, the underlying …

Tissue factor (TF) is a transmembrane glycoprotein and an essential component of the factor
VIIa‐TF enzymatic complex that triggers activation of the coagulation cascade. Formation of …

Sepsis is invariably accompanied by altered coagulation cascade; however, the precise role
of phosphatidylserine (PS) in inflammation-associated coagulopathy in sepsis has not been …

The pleiotropic activity of human cathelicidin LL-37 peptide includes an ability to suppress
development of colon cancer cells. We hypothesized that the anticancer activity of LL-37 …

The rate of complete remission of acute promyelocytic leukemia (APL) is currently over 90%
because of the use of all-trans retinoic acid (ATRA) with arsenic trioxide (ATO). However …