Alzheimer's disease (AD) is a prevalently found tauopathy characterized by memory loss
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …

Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in
membrane remodelling, has a critical role in endocytic membrane fission events. The use of …

Membranes are flexible barriers that surround the cell and its compartments. To execute vital
functions such as locomotion or receptor turnover, cells need to control the shapes of their …

All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …

Research investigating lipid membrane curvature generation and sensing is a rapidly
developing frontier in membrane physical chemistry and biophysics. The fast recent …

Biological membranes undergo constant remodeling by membrane fission and fusion to
change their shape and to exchange material between subcellular compartments. During …

Mechanisms that ensure robust long-term performance of synaptic transmission over a wide
range of activity are crucial for the integrity of neuronal networks, for processing sensory …

Actin filament assembly typically occurs in association with cellular membranes. A large
number of proteins sit at the interface between actin networks and membranes, playing …

Against the odds of membrane resistance, members of the BIN/Amphiphysin/Rvs (BAR)
domain superfamily shape membranes and their activity is indispensable for a plethora of …

Dynamin mediates fission of vesicles from the plasma membrane during endocytosis.
Typically, dynamin is recruited from the cytosol to endocytic sites, requiring seconds to tens …