Cognition is defined as the brain's ability to acquire, process, store, and retrieve information.
Pain has been described as an unpleasant sensory or emotional experience, and for …

Background This position statement provides clinical recommendations for the assessment
of pain, level of sedation, iatrogenic withdrawal syndrome and delirium in critically ill infants …

OBJECTIVE: To develop comprehensive clinical practice guidelines for critically ill infants
and children, with specific attention to seven domains of care including pain …

Newborn infants experience acute pain with various medical procedures. Evidence
demonstrates that controlling pain in the newborn period is beneficial, improving …

Routine assessment and management of neonatal pain has evolved to become an
important therapeutic goal in the twenty-first century. During the twentieth century, however …

Importance Protocolized sedation improves clinical outcomes in critically ill adults, but its
effect in children is unknown. Objective To determine whether critically ill children managed …

Opioid Tolerance in Critical Illness | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Abstract Mu-Opioid Receptors (MORs) are well-known for participating in analgesia,
sedation, drug addiction, and other physiological functions. Although MORs have been …

The prevention, assessment, and treatment of neonatal pain and agitation continues to
challenge clinicians and researchers. Substantial progress has been made in the past three …

Problem Current research suggests behavioral and environmental interventions to prevent
neonatal pain prior to an invasive procedure are rarely administered and seldom …