Spatial normalization and quantification approaches of PET imaging for neurological disorders

T Zhang, S Wu, X Zhang, Y Dai, A Wang… - European Journal of …, 2022 - Springer
Quantification approaches of positron emission tomography (PET) imaging provide user-
independent evaluation of pathophysiological processes in living brains, which have been …

A survey on computer-aided diagnosis of brain disorders through MRI based on machine learning and data mining methodologies with an emphasis on Alzheimer …

L Lazli, M Boukadoum, OA Mohamed - Applied Sciences, 2020 - mdpi.com
Computer-aided diagnostic (CAD) systems use machine learning methods that provide a
synergistic effect between the neuroradiologist and the computer, enabling an efficient and …

PETPVE12: an SPM toolbox for partial volume effects correction in brain PET–application to amyloid imaging with AV45-PET

G Gonzalez-Escamilla, C Lange, S Teipel, R Buchert… - Neuroimage, 2017 - Elsevier
Positron emission tomography (PET) allows detecting molecular brain changes in vivo.
However, the accuracy of PET is limited by partial volume effects (PVE) that affects …

Implementing the centiloid transformation for 11C-PiB and β-amyloid 18F-PET tracers using CapAIBL

P Bourgeat, V Doré, J Fripp, D Ames, CL Masters… - Neuroimage, 2018 - Elsevier
The centiloid scale was recently proposed to provide a standard framework for the
quantification of β-amyloid PET images, so that amyloid burden can be expressed on a …

Generation of structural MR images from amyloid PET: application to MR-less quantification

H Choi, DS Lee - Journal of Nuclear Medicine, 2018 - Soc Nuclear Med
Structural MR images concomitantly acquired with PET images can provide crucial anatomic
information for precise quantitative analysis. However, in the clinical setting, not all the …

Comparison of MR-less PiB SUVR quantification methods

P Bourgeat, VL Villemagne, V Dore, B Brown… - Neurobiology of …, 2015 - Elsevier
Abstract 11 C-Pittsburgh compound B (PiB) is a positron emission tomography (PET) tracer
designed to bind to amyloid-β (Aβ) plaques, one of the hallmarks of Alzheimer's disease …

rPOP: robust PET-only processing of community acquired heterogeneous amyloid-PET data

L Iaccarino, R La Joie, R Koeppe, BA Siegel, BE Hillner… - Neuroimage, 2022 - Elsevier
The reference standard for amyloid-PET quantification requires structural MRI (sMRI) for
preprocessing in both multi-site research studies and clinical trials. Here we describe rPOP …

Comparison of 18F-florbetaben quantification results using the standard Centiloid, MR-based, and MR-less CapAIBL® approaches: Validation against histopathology

V Doré, S Bullich, CC Rowe, P Bourgeat, S Konate… - Alzheimer's & …, 2019 - Elsevier
Introduction 18 F-florbetaben is currently approved for the visual rule out of β-amyloid (Aβ)
pathology. It is also used for recruitment and as an outcome measure in therapeutic trials …

A semiautomated method for quantification of F 18 florbetapir PET images

AD Joshi, MJ Pontecorvo, M Lu… - Journal of Nuclear …, 2015 - Soc Nuclear Med
PET amyloid imaging is increasingly used in research trials related to Alzheimer disease
and has potential as a quantitative biomarker. This study had 3 objectives: first, to describe a …

Quantification of amyloid beta and tau PET without a structural MRI

SM Landau, TJ Ward, A Murphy… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Relying on magnetic resonance imaging (MRI) for quantification of positron
emission tomography (PET) images may limit generalizability of the results. We evaluated …