Neuroinflammatory mechanisms in ischemic stroke: focus on cardioembolic stroke, background, and therapeutic approaches

CD Maida, RL Norrito, M Daidone… - International journal of …, 2020 - mdpi.com
One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …

The role of selected pro-inflammatory cytokines in pathogenesis of ischemic stroke

H Pawluk, A Woźniak, G Grześk… - … interventions in aging, 2020 - Taylor & Francis
Stroke is currently one of the most common causes of death and disability in the world, and
its pathophysiology is a complex process, involving the oxidative stress and inflammatory …

[HTML][HTML] Role of lipocalin 2 in stroke

RY Zhao, PJ Wei, X Sun, DH Zhang, QY He, J Liu… - Neurobiology of …, 2023 - Elsevier
Stroke is the second leading cause of death worldwide; however, the treatment choices
available to neurologists are limited in clinical practice. Lipocalin 2 (LCN2) is a secreted …

Investigating the potential mechanisms and therapeutic targets of inflammatory cytokines in post-stroke depression

Y Zhang, Y Yang, H Li, Q Feng, W Ge, X Xu - Molecular Neurobiology, 2024 - Springer
Post-stroke depression (PSD) affects approximately one-third of stroke survivors, severely
impacting general recovery and quality of life. Despite extensive studies, the exact …

Biomarkers of unfavorable outcome in acute ischemic stroke patients with successful recanalization by endovascular thrombectomy

N Zang, Z Lin, K Huang, Y Pan, Y Wu, Y Wu… - Cerebrovascular …, 2020 - karger.com
Background: We aimed to identify plasma markers of unfavorable outcomes for patients with
acute ischemic stroke (AIS) after recanalization by endovascular thrombectomy (EVT) …

The trends in nanomaterial-based biosensors for detecting critical biomarkers in stroke

S Dolati, J Soleymani, SK Shakouri, A Mobed - Clinica chimica acta, 2021 - Elsevier
Acute ischemic stroke (AIS), is the second global cause of death after cardiovascular
diseases, accounts for 80–85% of cerebrovascular disease. Stroke diagnosis could be …

Selected mediators of inflammation in patients with acute ischemic stroke

H Pawluk, R Kołodziejska, G Grześk… - International Journal of …, 2022 - mdpi.com
During a stroke, a series of biochemical and metabolic changes occur which eventually lead
to the death of cells by necrosis or apoptosis. This is a multi-stage process involving …

Hypoxia induces astrocyte-derived lipocalin-2 in ischemic stroke

F Ranjbar Taklimie, N Gasterich, M Scheld… - International journal of …, 2019 - mdpi.com
Ischemic stroke causes rapid hypoxic damage to the core neural tissue which is followed by
graded chronological tissue degeneration in the peri-infarct zone. The latter process is …

A systematic review of the predictive value of plasma D-dimer levels for predicting stroke outcome

P Zhang, C Wang, J Wu, S Zhang - Frontiers in Neurology, 2021 - frontiersin.org
Background: Stroke is a leading cause of morbidity and mortality. Over the past decade,
plasma D-dimer levels have emerged as a biomarker for predicting stroke outcome …

Clinical significance of plasma D-dimer and fibrinogen in outcomes after stroke: a systematic review and meta-analysis

QJ Bao, JN Zhang, XT Wu, K Zhao, Y Guo… - Cerebrovascular …, 2023 - karger.com
Background: There is increasing evidence on the prognostic significance of D-dimer and
fibrinolysis in stroke. However, the systematic analysis of their relationship with adverse …