Lensless imaging and sensing

A Ozcan, E McLeod - Annual review of biomedical engineering, 2016 - annualreviews.org
High-resolution optical microscopy has traditionally relied on high-magnification and high–
numerical aperture objective lenses. In contrast, lensless microscopy can provide high …

Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy

A Greenbaum, W Luo, TW Su, Z Göröcs, L Xue… - Nature …, 2012 - nature.com
We discuss unique features of lens-free computational imaging tools and report some of
their emerging results for wide-field on-chip microscopy, such as the achievement of a …

Lensless digital holographic microscopy and its applications in biomedicine and environmental monitoring

Y Wu, A Ozcan - Methods, 2018 - Elsevier
Optical compound microscope has been a major tool in biomedical imaging for centuries. Its
performance relies on relatively complicated, bulky and expensive lenses and alignment …

Optical imaging techniques for point-of-care diagnostics

H Zhu, SO Isikman, O Mudanyali, A Greenbaum… - Lab on a Chip, 2013 - pubs.rsc.org
Improving access to effective and affordable healthcare has long been a global endeavor. In
this quest, the development of cost-effective and easy-to-use medical testing equipment that …

Maskless imaging of dense samples using pixel super-resolution based multi-height lensfree on-chip microscopy

A Greenbaum, A Ozcan - Optics express, 2012 - opg.optica.org
Lensfree in-line holographic microscopy offers sub-micron resolution over a large field-of-
view (eg,~ 24 mm^ 2) with a cost-effective and compact design suitable for field use …

Theoretical and experimental demonstration of resolution beyond the Rayleigh limit by FINCH fluorescence microscopic imaging

J Rosen, N Siegel, G Brooker - Optics express, 2011 - opg.optica.org
Fresnel Incoherent Correlation Holography (FINCH) enables holograms to be recorded from
incoherent light with just a digital camera and spatial light modulator. We previously …

Wide-field optical detection of nanoparticles using on-chip microscopy and self-assembled nanolenses

O Mudanyali, E McLeod, W Luo, A Greenbaum… - Nature …, 2013 - nature.com
The direct observation of nanoscale objects is a challenging task for optical microscopy
because the scattering from an individual nanoparticle is typically weak at optical …

Unconventional methods of imaging: computational microscopy and compact implementations

E McLeod, A Ozcan - Reports on Progress in Physics, 2016 - iopscience.iop.org
In the past two decades or so, there has been a renaissance of optical microscopy research
and development. Much work has been done in an effort to improve the resolution and …

Resolution enhancement in quantitative phase microscopy

V Micó, J Zheng, J Garcia, Z Zalevsky… - Advances in Optics and …, 2019 - opg.optica.org
Quantitative phase microscopy (QPM), a technique combining phase imaging and
microscopy, enables visualization of the 3D topography in reflective samples, as well as the …

On-chip biomedical imaging

Z Göröcs, A Ozcan - IEEE reviews in biomedical engineering, 2012 - ieeexplore.ieee.org
Lab-on-a-chip systems have been rapidly emerging to pave the way toward ultra-compact,
efficient, mass producible and cost-effective biomedical research and diagnostic tools …