Molecular and cellular heterogeneity in rheumatoid arthritis: mechanisms and clinical implications

J Zhao, S Guo, SJ Schrodi, D He - Frontiers in immunology, 2021 - frontiersin.org
Rheumatoid arthritis is an autoimmune disease that exhibits significant clinical
heterogeneity. There are various treatments for rheumatoid arthritis, including disease …

Novel insight into the mechanisms of the bidirectional relationship between diabetes and periodontitis

F Barutta, S Bellini, M Durazzo, G Gruden - Biomedicines, 2022 - mdpi.com
Periodontitis and diabetes are two major global health problems despite their prevalence
being significantly underreported and underestimated. Both epidemiological and …

Oral, tongue-coating microbiota, and metabolic disorders: a novel area of interactive research

Y Li, J Cui, Y Liu, K Chen, L Huang… - Frontiers in cardiovascular …, 2021 - frontiersin.org
Interactions between colonizing microbiota and the host have been fully confirmed, among
which the tongue-coating microbiota have a moderate rate of renewal and disease …

Periodontal disease in pregnancy and adverse pregnancy outcomes: Progress in related mechanisms and management strategies

M Nannan, L Xiaoping, J Ying - Frontiers in Medicine, 2022 - frontiersin.org
Periodontal disease is an inflammatory and destructive disease of tissues supporting the
tooth. A large number of studies have confirmed that periodontal pathogens and their …

Oral and Gut Microbial Dysbiosis and Non-alcoholic Fatty Liver Disease: The Central Role of Porphyromonas gingivalis

T Wang, T Ishikawa, M Sasaki, T Chiba - Frontiers in medicine, 2022 - frontiersin.org
Gut microbiota play many important roles, such as the regulation of immunity and barrier
function in the intestine, and are crucial for maintaining homeostasis in living organisms. The …

Porphyromonas gingivalis outer membrane vesicles as the major driver of and explanation for neuropathogenesis, the cholinergic hypothesis, iron dyshomeostasis …

PL Nara, D Sindelar, MS Penn… - Journal of …, 2021 - content.iospress.com
Porphyromonas gingivalis (Pg) is a primary oral pathogen in the widespread biofilm-induced
“chronic” multi-systems inflammatory disease (s) including Alzheimer's disease (AD). It is …

The Effects of Porphyromonas gingivalis on Atherosclerosis-Related Cells

J Zhang, M Xie, X Huang, G Chen, Y Yin, X Lu… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis (AS), one of the most common types of cardiovascular disease, has initially
been attributed to the accumulation of fats and fibrous materials. However, more and more …

[HTML][HTML] Outer membrane vesicles of Porphyromonas gingivalis: Novel communication tool and strategy

H Okamura, K Hirota, K Yoshida, Y Weng, Y He… - … Dental Science Review, 2021 - Elsevier
Extracellular vesicles (EVs) have been recognized as a universal method of cellular
communications and are reportedly produced in bacteria, archaea, and eukaryotes …

The bidirectional relationship between periodontal disease and pregnancy via the interaction of oral microorganisms, hormone and immune response

X Wen, X Fu, C Zhao, L Yang, R Huang - Frontiers in Microbiology, 2023 - frontiersin.org
Periodontal disease has been suggested to be linked to adverse pregnancy outcomes such
as preterm birth, low birth weight, and preeclampsia. Adverse pregnancy outcomes are a …

Procyanidins and their therapeutic potential against oral diseases

H Chen, W Wang, S Yu, H Wang, Z Tian, S Zhu - Molecules, 2022 - mdpi.com
Procyanidins, as a kind of dietary flavonoid, have excellent pharmacological properties,
such as antioxidant, antibacterial, anti-inflammatory and anti-tumor properties, and so they …