Insulin resistance is a systemic disorder that affects many organs and insulin-regulated
pathways. The disorder is characterized by a reduced action of insulin despite increased …

Diabetes mellitus contributes greatly to morbidity, mortality, and overall health care costs. In
major part, these outcomes derive from the high incidence of progressive kidney dysfunction …

The serum-and glucocorticoid-inducible kinase-1 (SGK1) is ubiquitously expressed and
under genomic control by cell stress (including cell shrinkage) and hormones (including …

The Western-style diet is characterized by its highly processed and refined foods and high
contents of sugars, salt, and fat and protein from red meat. It has been recognized as the …

Introduction: Glycemic control is important in diabetes mellitus to minimize the progression of
the disease and the risk of potentially devastating complications. Inhibition of the sodium …

Diabetic nephropathy seems to occur as a result of an interaction of metabolic and
haemodynamic factors. Glucose dependent pathways are activated within the diabetic …

Aldosterone controls sodium reabsorption and potassium secretion in the aldosterone-
sensitive distal nephron (ASDN). Although clearance measurements have shown that …

The serum-and glucocorticoid-regulated kinase (sgk1) is induced by mineralocorticoids and,
in turn, upregulates heterologously expressed renal epithelial Na+ channel (ENaC) activity …

The ubiquitously expressed serum‐and glucocorticoid‐inducible kinase‐1 (SGK1) is
genomically regulated by cell stress (including cell shrinkage) and several hormones …

Creatine monohydrate (CrM) supplementation during resistance exercise training results in
a greater increase in strength and fat-free mass than placebo. Whether this is solely due to …