By eliciting distinct transcriptional responses, the oestrogen receptors (ERs) ERα and ERβ
exert opposite effects on cellular processes that include proliferation, apoptosis and …

Estrogen receptors are broadly expressed in many cell types involved in the innate and
adaptive immune responses, and differentially regulate the production of cytokines. While …

Estrogen has been postulated as a contributor for lung cancer development and
progression. We reviewed the current knowledge about the expression and prognostic …

Sex differences in the biology of different organ systems and the influence of sex hormones
in modulating health and disease are increasingly relevant in clinical and research areas …

Summary Monocarboxylate transporter 1 (MCT1) inhibition is thought to block tumor growth
through disruption of lactate transport and glycolysis. Here, we show MCT1 inhibition …

The involvement of estrogen and its receptors in the development of cancer has been known
for years. However, the exact mechanism responsible is far from clear. The estrogen …

Context: Low testosterone is associated with all-cause mortality, but the relationship with
cause-specific mortality is uncertain. Objective: Our objective was to explore associations …

Purpose: Steroid hormones and growth factors affect lung cancer, and it is possible they act
in concert to influence patient outcome. Experimental Design: Primary lung tumors and …

Lung cancer mortality represents the leading cause of cancer related deaths in the United
States and worldwide. Almost half of these deaths occur in female patients, making lung …

Purpose: The possible involvement of gender-dependent factors has been suggested in
human non-small cell lung carcinomas (NSCLC), but their precise roles remain largely …