1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Phenols and phenolic ethers are significant scaffolds recurring both in nature and among
approved small-molecule pharmaceuticals. This compendium presents the first …

The biocatalytic transformations used by chemists are often restricted to simple functional-
group interconversions. In contrast, nature has developed complexity-generating biocatalytic …

This review describes the additions of allylmagnesium reagents to carbonyl compounds and
to imines, focusing on the differences in reactivity between allylmagnesium halides and …

Type II intramolecular cycloadditions ([4+ 2],[4+ 3],[4+ 4] and [5+ 2]) have emerged recently
as an efficient and powerful strategy for the construction of bridged ring systems. In general …

A new strategy was developed for the asymmetric total synthesis of (−)-vinigrol. The strategy
involved a linear sequence of 15 steps from 3-methyl-butanal (14 steps from chloro …

Oxidative Se‐catalyzed C (sp3) H bond acyloxylation has been used to construct a diverse
array of isobenzofuranones from simple ortho‐allyl benzoic acid derivatives. The synthetic …

Biocatalytic reactions embody many features of ideal chemical transformations, including the
potential for impeccable selectivity, high catalytic efficiency, mild reaction conditions, and the …

Vinigrol is a structurally and stereochemically complex diterpenoid that displays various
potent pharmacological activities. Two generations of synthetic routes were designed and …

A metal‐free, one‐pot synthesis of 1, 2‐naphthoquinone was accomplished from 2‐naphthol
by utilizing economically cheap NBS under open air conditions. Initial formation of 1, 1 …