Epilepsy is a chronic neurological condition characterized by recurrent seizures that affects
millions of people worldwide. Comprehension of the complex mechanisms underlying …

Epilepsy is a common and serious neurologic disease with a strong genetic component.
Genetic studies have identified an increasing collection of disease-causing genes. The …

Chronic fatigue is a typical symptom of neurological diseases, and is most disabling in
multiple sclerosis, postpoliomyelitis, poststroke, and in chronic fatigue syndrome. Disorders …

This review considers how recent advances in the physiology of ion channels and other
potential molecular targets, in conjunction with new information on the genetics of idiopathic …

The molecular basis of idiopathic generalized epilepsy remains poorly understood. Absence
epilepsy with 3 Hz spike–wave EEG is one of the most common human epilepsies, and is …

Autophagy helps deliver sequestered intracellular cargo to lysosomes for proteolytic
degradation and thereby maintains cellular homeostasis by preventing accumulation of toxic …

Voltage‐gated calcium channels (VGCCs) represent the sole mechanism to convert
membrane depolarization into cellular functions like secretion, contraction, or gene …

The Food Quality Protection Act of 1996 requires that the US Environmental Protection
Agency conduct cumulative risk assessments for classes of pesticides that have a common …

Absence epilepsy, a disease predominantly of childhood, has long been known to arise from
an aberration of the interplay between two brain regions, the cortex and the thalamus …

Epilepsy, a heterogeneous group of brain-related diseases, has continued to significantly
burden society and families. Epilepsy comorbid with neurodevelopmental disorders (NDDs) …