Dysregulated signaling at postsynaptic density: A systematic review and translational appraisal for the pathophysiology, clinics, and antipsychotics' treatment of …

A de Bartolomeis, L Vellucci, G De Simone, B Mazza… - Cells, 2023 - mdpi.com
Emerging evidence from genomics, post-mortem, and preclinical studies point to a potential
dysregulation of molecular signaling at postsynaptic density (PSD) in schizophrenia …

Research progress on the correlation between epigenetics and schizophrenia

Q Chen, D Li, W Jin, Y Shi, Z Li, P Ma, J Sun… - Frontiers in …, 2021 - frontiersin.org
Purpose of the Review Nowadays, the incidence of schizophrenia is noticeably increased. If
left undiagnosed and untreated, it will lead to impaired social functions, repeated hospital …

DNA methylation in stress and depression: from biomarker to therapeutics

AJ Sales, FS Guimarães, SRL Joca - Acta Neuropsychiatrica, 2021 - cambridge.org
Epigenetic mechanisms such as DNA methylation (DNAm) have been associated with stress
responses and increased vulnerability to depression. Abnormal DNAm is observed in …

Schizophrenia as metabolic disease. What are the causes?

AMN Helaly, DSED Ghorab - Metabolic Brain Disease, 2023 - Springer
Schizophrenia (SZ) is a devastating neurodevelopmental disease with an accelerated
ageing feature. The criteria of metabolic disease firmly fit with those of schizophrenia …

Transcriptome and DNA methylation analysis of the goat pineal gland during puberty

B Zhang, G Zhu, J Wu, H Xie, J Cui, W Qian, Q Yi… - Scientific Reports, 2025 - nature.com
Previous studies have confirmed that methylation regulates gene transcription in the
hypothalamus-pituitary-gonadal axis during puberty initiation, but little is known about the …

[HTML][HTML] Altered mRNA expression levels of autophagy-and apoptosis-related genes in the FOXO pathway in schizophrenia patients treated with olanzapine

S Gu, F Cui, J Yin, C Fang, L Liu - Neuroscience Letters, 2021 - Elsevier
This study attempted to analyze the alterations in the mRNA expression levels of autophagy-
and apoptosis-related genes in the forkhead box transcription factor O (FOXO) pathway in …

Fish as model systems to study epigenetic drivers in human self-domestication and neurodevelopmental cognitive disorders

D Anastasiadi, F Piferrer, M Wellenreuther… - Genes, 2022 - mdpi.com
Modern humans exhibit phenotypic traits and molecular events shared with other
domesticates that are thought to be by-products of selection for reduced aggression. This is …

Genome-wide DNA methylation analysis in schizophrenia with tardive dyskinesia: a preliminary study

P Zhang, Y Lu, Y Li, K Wang, H An, Y Tan - Genes & Genomics, 2023 - Springer
Background Tardive dyskinesia (TD) develops in 20–30% of schizophrenia patients and up
to 50% in patients> 50 years old. DNA methylation may play an important role in the …

Infección por Toxoplasma gondii como factor de riesgo para desarrollar esquizofrenia: revisión de la literatura

FB Rodríguez, AM Zárate, DC Martínez… - Universitas …, 2023 - revistas.javeriana.edu.co
La esquizofrenia es un trastorno incapacitante del neurodesarrollo con una prevalencia a lo
largo de la vida del 1%. Algunos estudios han relacionado diversas enfermedades …

[HTML][HTML] Schizophrenia Susceptibility Genes

BN Akı, O Erbaş - Journal of Experimental and Basic Medical Sciences, 2022 - jebms.org
Schizophrenia is an inherited condition, and studies have revealed that environmental
influences have a greater genetic effect. Histone modification is related to deoxyribonucleic …