MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …

Mammalian oocytes go through a long and complex developmental process while acquiring
the competencies that are required for fertilization and embryogenesis. Recent advances in …

Full-grown oocytes are transcriptionally silent and must stably maintain the messenger
RNAs (mRNAs) needed for oocyte meiotic maturation and early embryonic development …

YTHDF2 binds and destabilizes N 6-methyladenosine (m 6 A)-modified mRNA. The extent to
which this branch of m 6 A RNA-regulatory pathway functions in vivo and contributes to …

MicroRNAs are small non‐coding RNA guide molecules that regulate gene expression via
association with effector complexes and sequence‐specific recognition of target sites on …

Fertilization triggers a complex cellular programme that transforms two highly specialized
meiotic germ cells, the oocyte and the sperm, into a totipotent mitotic embryo. Linkages …

In mammals, a single Dicer participates in biogenesis of small RNAs in microRNA (miRNA)
and RNAi pathways. In mice, endogenous RNAi is highly active in oocytes, but not in …

So far, the characteristics of a good quality egg have been elusive, similar to the nature of
the physiological, cellular, and molecular cues leading to its production both in vivo and in …

Maternal mRNAs are essential for protein synthesis during oogenesis and early
embryogenesis. To adapt translation to specific needs during development, maternal …

MicroRNAs (miRNAs) are small endogenous RNAs that typically imperfectly base pair with
3′ untranslated regions (3′ UTRs) and mediate translational repression and mRNA …