Evolutionary insights into host–pathogen interactions from mammalian sequence data

M Sironi, R Cagliani, D Forni, M Clerici - Nature Reviews Genetics, 2015 - nature.com
Infections are one of the major selective pressures acting on humans, and host-pathogen
interactions contribute to shaping the genetic diversity of both organisms. Evolutionary …

Global parasite and Rattus rodent invasions: The consequences for rodent‐borne diseases

S Morand, F Bordes, HW CHEN, J Claude… - Integrative …, 2015 - Wiley Online Library
We summarize the current knowledge on parasitism‐related invasion processes of the
globally invasive Rattus lineages, originating from Asia, and how these invasions have …

Toll-like receptor evolution in birds: gene duplication, pseudogenization, and diversifying selection

H Velová, MW Gutowska-Ding, DW Burt… - … Biology and Evolution, 2018 - academic.oup.com
Toll-like receptors (TLRs) are key sensor molecules in vertebrates triggering initial phases of
immune responses to pathogens. The avian TLR family typically consists of ten receptors …

Episodic positive selection in the evolution of avian toll-like receptor innate immunity genes

CE Grueber, GP Wallis, IG Jamieson - PLoS One, 2014 - journals.plos.org
Toll-like receptors (TLRs) are a family of conserved pattern-recognition molecules
responsible for initiating innate and acquired immune responses. Because they play a key …

Drift, not selection, shapes toll‐like receptor variation among oceanic island populations

C Gonzalez‐Quevedo, LG Spurgin, JC Illera… - Molecular …, 2015 - Wiley Online Library
Understanding the relative role of different evolutionary forces in shaping the level and
distribution of functional genetic diversity among natural populations is a key issue in …

Adaptation and cryptic pseudogenization in penguin toll-like receptors

SR Fiddaman, M Vinkler, SG Spiro… - Molecular Biology …, 2022 - academic.oup.com
Penguins (Sphenisciformes) are an iconic order of flightless, diving seabirds distributed
across a large latitudinal range in the Southern Hemisphere. The extensive area over which …

Signatures of balancing selection in toll-like receptor (TLRs) genes–novel insights from a free-living rodent

A Kloch, MA Wenzel, DR Laetsch, O Michalski… - Scientific Reports, 2018 - nature.com
Selective pressure from pathogens is considered a key selective force driving the evolution
of components of the immune system. Since single components of the immune system may …

Immunogenetic heterogeneity in a widespread ungulate: the European roe deer (Capreolus capreolus)

E Quéméré, M Galan, JF Cosson, F Klein… - Molecular …, 2015 - Wiley Online Library
Understanding how immune genetic variation is shaped by selective and neutral processes
in wild populations is of prime importance in both evolutionary biology and epidemiology …

The evolution of bat nucleic acid‐sensing Toll‐like receptors

M Escalera‐Zamudio, ML Zepeda‐Mendoza… - Molecular …, 2015 - Wiley Online Library
We characterized the nucleic acid‐sensing Toll‐like receptors (TLR) of a New World bat
species, the common vampire bat (Desmodus rotundus), and through a comparative …

An evolutionary perspective of nutrition and inflammation as mechanisms of cardiovascular disease

ME Rubio-Ruiz, AE Peredo-Escárcega… - International journal …, 2015 - Wiley Online Library
When cardiovascular diseases are viewed from an evolutionary biology perspective, a
heightened thrifty and an inflammatory design could be their mechanisms. Human ancestors …