A comprehensive neural simulation of slow-wave sleep and highly responsive wakefulness dynamics

JS Goldman, L Kusch, D Aquilue… - Frontiers in …, 2023 - frontiersin.org
Hallmarks of neural dynamics during healthy human brain states span spatial scales from
neuromodulators acting on microscopic ion channels to macroscopic changes in …

Biologically realistic mean-field models of conductance-based networks of spiking neurons with adaptation

M Di Volo, A Romagnoni, C Capone… - Neural computation, 2019 - direct.mit.edu
Accurate population models are needed to build very large-scale neural models, but their
derivation is difficult for realistic networks of neurons, in particular when nonlinear properties …

[HTML][HTML] Awake perception is associated with dedicated neuronal assemblies in the cerebral cortex

A Filipchuk, J Schwenkgrub, A Destexhe… - Nature …, 2022 - nature.com
Neural activity in the sensory cortex combines stimulus responses and ongoing activity, but it
remains unclear whether these reflect the same underlying dynamics or separate processes …

Brain-scale emergence of slow-wave synchrony and highly responsive asynchronous states based on biologically realistic population models simulated in The Virtual …

JS Goldman, L Kusch, BH Yalcinkaya… - BioRxiv, 2020 - biorxiv.org
Understanding the many facets of the organization of brain dynamics at large scales
remains largely unexplored. Here, we construct a brain-wide model based on recent …

Bridging single neuron dynamics to global brain states

JS Goldman, N Tort-Colet, M Di Volo… - Frontiers in systems …, 2019 - frontiersin.org
Biological neural networks produce information backgrounds of multi-scale spontaneous
activity that become more complex in brain states displaying higher capacities for cognition …

Space-time dynamics of membrane currents evolve to shape excitation, spiking, and inhibition in the cortex at small and large scales

PE Roland - Neuron, 2017 - cell.com
In the cerebral cortex, membrane currents, ie, action potentials and other membrane
currents, express many forms of space-time dynamics. In the spontaneous asynchronous …

Suppressive traveling waves shape representations of illusory motion in primary visual cortex of awake primate

S Chemla, A Reynaud, M Di Volo, Y Zerlaut… - Journal of …, 2019 - Soc Neuroscience
How does the brain link visual stimuli across space and time? Visual illusions provide an
experimental paradigm to study these processes. When two stationary dots are flashed in …

A mean-field approach to the dynamics of networks of complex neurons, from nonlinear Integrate-and-Fire to Hodgkin–Huxley models

M Carlu, O Chehab, L Dalla Porta… - Journal of …, 2020 - journals.physiology.org
We present a mean-field formalism able to predict the collective dynamics of large networks
of conductance-based interacting spiking neurons. We apply this formalism to several …

Spontaneous traveling waves naturally emerge from horizontal fiber time delays and travel through locally asynchronous-irregular states

ZW Davis, GB Benigno, C Fletterman… - Nature …, 2021 - nature.com
Studies of sensory-evoked neuronal responses often focus on mean spike rates, with
fluctuations treated as internally-generated noise. However, fluctuations of spontaneous …

Experimental and computational study on motor control and recovery after stroke: toward a constructive loop between experimental and virtual embodied …

AL Allegra Mascaro, E Falotico, S Petkoski… - Frontiers in systems …, 2020 - frontiersin.org
Being able to replicate real experiments with computational simulations is a unique
opportunity to refine and validate models with experimental data and redesign the …