Y Kong, W Wang, C Wang, L Li, D Peng… - International Journal of …, 2023 - Elsevier
Amorphous solid dispersion (ASD) is a promising strategy to enhance solubility and bioavailability of poorly water-soluble drugs. Due to higher free energy of ASD …
According to the Scopus database, every year several hundreds of new research papers are published in the field of nanofluids. This area is attracting growing attention because of the …
A Kabedev, X Zhuo, D Leng, V Foderà… - Molecular …, 2022 - ACS Publications
Proteins, and in particular whey proteins, have recently been introduced as a promising excipient class for stabilizing amorphous solid dispersions. However, despite the efficacy of …
S Dohrn, SO Kyeremateng, E Bochmann, E Sobich… - Pharmaceutics, 2023 - mdpi.com
During the dissolution of amorphous solid dispersion (ASD) formulations, the gel layer that forms at the ASD/water interface strongly dictates the release of the active pharmaceutical …
Robust and reliable in vivo performance of medicines based on amorphous solid dispersions (ASDs) depend on maintenance of physical stability and efficient …
T Casalini, J Mann, X Pepin - Molecular Pharmaceutics, 2023 - ACS Publications
Dissolution of ionizable drugs and their salts is a function of drug surface solubility driven by the surface pH, ie, the microenvironmental pH at the solid/liquid interface, which will deviate …
LM Lim, JW Park, K Hadinoto - Pharmaceutics, 2022 - mdpi.com
Amorphization, typically in the form of amorphous solid dispersion (ASD), represents a well- established solubility enhancement strategy for poorly soluble drugs. Recently, two …
K Chen, K Zeng - Mobile Information Systems, 2022 - Wiley Online Library
Molecular dynamics simulation is an effective method for related research in the microscopic world, mainly related to molecular atomic research, and it has a wide range of applications …
CA Lohmann, E Sobich, ES Bochmann… - J Anal Pharm …, 2022 - researchgate.net
Sodium carboxymethylcellulose (NaCMC) is used as excipient in several marketed products from the biopharmaceutical and food industries owing to its non-toxic biocompatible nature …