The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Vascular and immune dysfunctions are thought to be related to the pathogenesis of
inflammatory bowel disease (IBD), but behind this, the exact mechanism of mucosal …

Obesity is defined as abnormal or excessive accumulation of adipose tissue, closely
associated with the increased risk of various comorbidities, especially type 2 diabetes …

DGC is a particular aggressive malignancy with poor prognosis. Recent omics studies
characterized DGC with CDH1/E-cadherin loss and EMT-signatures. However, the …

Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders
but remains relatively under-studied compared with other biological fluids such as plasma …

Neurexins are presynaptic adhesion molecules that organize synapses by binding to
diverse trans-synaptic ligands, but how neurexins are regulated is incompletely understood …

Sphingosine 1-phosphate (S1P), derived from membrane sphingolipids, is a pleiotropic
bioactive lipid mediator capable of evoking complex immune phenomena. Studies have …

With the increasing prevalence of obesity, obesity-related problems such as cardiometabolic
disorders (CMD), are also rapidly increasing. To prevent and alleviate the progressive …

Background and aims Novel pro-and anti-inflammatory adipocytokines affect inflammation,
energy metabolism, and insulin signaling. However, their role in acute coronary syndrome …