The obesity epidemic has become a global public health crisis in recent years and is
continuing to worsen at an alarming rate. However, the pathophysiological mechanisms …

Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …

The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

Ammonia has been long recognized as a metabolic waste product with well-known
neurotoxic effects. However, little is known about the beneficial function of endogenous …

Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a
risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various …

Feeding behaviors depend on intrinsic and extrinsic factors including genetics, food
palatability, and the environment. 1, 2, 3, 4, 5 The gut microbiota is a major environmental …

Direct evidence in humans for the impact of the microbiome on nutrient absorption is lacking.
We conducted an extended inpatient study using two interventions that we hypothesized …

In recent years, studies investigating the role of the gut microbiota in health and diseases
have increased enormously–making it essential to deepen and question the research …

The fruits of citrus family are rich in flavonoids with superior antioxidant properties; citrus
bioactive components are potentially beneficial without adverse effects or cytotoxicity in …

Genetic variants are traditionally known to shape the susceptibility to neuropsychiatric
disorders. An increasing number of studies indicate that remodeling of the gut microbiome …