Semaphorins were originally identified as axon-guidance molecules that function during
neuronal development. However, cumulative evidence indicates that semaphorins also …

Semaphorins are mainly known as guidance signals in development, acting through
receptors called Plexins. However, their role in cancer is rapidly emerging in the regulation …

Semaphorins are regulatory molecules that are linked to the modulation of several cancer
processes, such as angiogenesis, cancer cell invasiveness and metastasis, tumor growth …

Aims The goal of our study was to investigate the heterogeneity of cardiac macrophages
(CMφs) in mice with transverse aortic constriction (TAC) via single-cell sequencing and …

Ferritin is an iron-binding molecule, which comprises 24 subunits, heavy (FeH) and light
(FeL) subunits, suggested to have a pathogenic role by the 'hyperferritinemic syndrome'. In …

Cytokines are small, secreted proteins that control immune responses. Within the lung, they
can control host responses to injuries or infection, resulting in clearance of the insult, repair …

Aberrant fear is a cornerstone of several psychiatric disorders. Consequently, there is large
interest in elucidation of signaling mechanisms that link extracellular cues to changes in …

The axon guidance cues semaphorins (Semas) and their receptors plexins have been
shown to regulate both physiological and pathological angiogenesis. Sema4A plays an …

Semaphorins are a group of proteins that are divided into eight subclasses and identified by
a conserved Sema domain on their carboxyl terminus. Sema4A, 4C, and 4D are the …

The semaphorin family members were originally considered to play a role in
neurodevelopment, angiogenesis, tumor development, and metastasis. Over the past few …