Integrated Molecular and Histological Insights for Targeted Therapies in Mesenchymal Sinonasal Tract Tumors

CC Hoch, L Knoedler, S Knoedler… - Current Oncology …, 2024 - Springer
Abstract Purpose of Review This review aims to provide a comprehensive overview of
mesenchymal sinonasal tract tumors (STTs), a distinct subset of STTs. Despite their rarity …

Long-term outcome of primary clival chordomas: a single-center retrospective study with an emphasis on the timing of recurrences based on the primary treatment

S Hong, Y Shinya, A Mahajan, NN Laack… - Neurosurgical …, 2024 - thejns.org
OBJECTIVE This study aimed to provide data on extended outcomes in primary clival
chordomas, focusing on progression-free survival (PFS) and overall survival (OS) …

脊索瘤分子诊断及治疗的研究进展

王斌, 张亚中, 汤中建, 朱哲希, 白津 - 徐州医科大学学报, 2024 - xb.xzhmu.edu.cn
脊索瘤作为一种恶性程度较高的原发恶性肿瘤, 起源于胚胎残余脊索组织, 复发率高, 预后差.
目前相关研究已经发现包括Brachyury 基因等多个分子及信号通路参与脊索瘤的发生发展 …

Artificial intelligence–an aid for physicians in chordoma management? A systematic review of current applications

PM Łajczak, K Jóźwik - Oncology in Clinical Practice, 2024 - journals.viamedica.pl
Introduction. Chordoma, a rare neoplasm originating from the notochord, poses diagnostic
and therapeutic challenges due to its slow growth and complex anatomical locations. The …

Inhibition of Yes-Associated Protein (YAP) with Verteporfin Enhances Radiosensitivity in Chordoma by Inducing G2M Arrest and Inhibiting the DNA Damage …

OO Akinduro, PS Meade, P Schiapparelli, R Whitehead… - bioRxiv, 2024 - biorxiv.org
Chordomas are locally invasive cancers that are highly resistant to radiotherapy. The
Brachyury and Yes Associated Protein (YAP) regulatory axis has been implicated as the …

Machine Learning and Risk Prediction Tools in Neurosurgery: A Rapid Review

J Sherman, M DiLuna - 2024 - search.proquest.com
INTRODUCTION: Artificial intelligence (AI) and machine learning (ML) techniques have
become highly visible in society and medicine, with some AI/ML-enabled devices receiving …

Research progress in molecular diagnosis and treatment of chordoma

W Bin, Z Yazhong, T Zhongjian… - Journal of Xuzhou …, 2024 - xb.xzhmu.edu.cn
Chordoma, as a highly malignant primary tumor, originates from residual embryonic spinal
cord tissue, with a high recurrence rate and poor prognosis. Although current research has …