Antimicrobial secondary metabolites from agriculturally important bacteria as next-generation pesticides

C Keswani, HB Singh, C García-Estrada… - Applied Microbiology …, 2020 - Springer
The whole organisms can be packaged as biopesticides, but secondary metabolites
secreted by microorganisms can also have a wide range of biological activities that either …

Hfq: a multifaceted RNA chaperone involved in virulence

JR Feliciano, AM Grilo, SI Guerreiro, SA Sousa… - Future …, 2016 - Taylor & Francis
Hfq has emerged in recent years as a master regulator of gene expression in bacteria,
mainly due to its ability to mediate the interaction of small noncoding RNAs with their mRNA …

C-terminal domain of the RNA chaperone Hfq drives sRNA competition and release of target RNA

A Santiago-Frangos, K Kavita… - Proceedings of the …, 2016 - National Acad Sciences
The bacterial Sm protein and RNA chaperone Hfq stabilizes small noncoding RNAs
(sRNAs) and facilitates their annealing to mRNA targets involved in stress tolerance and …

Analysis of the genomic sequences and metabolites of Serratia surfactantfaciens sp. nov. YD25T that simultaneously produces prodigiosin and serrawettin W2

C Su, Z Xiang, Y Liu, X Zhao, Y Sun, Z Li, L Li, F Chang… - BMC genomics, 2016 - Springer
Background Gram-negative bacteria of the genus Serratia are potential producers of many
useful secondary metabolites, such as prodigiosin and serrawettins, which have potential …

CRISPR-Cas immunity is repressed by the LysR-type transcriptional regulator PigU

LM Smith, HG Hampton, MS Yevstigneyeva… - Nucleic acids …, 2024 - academic.oup.com
Bacteria protect themselves from infection by bacteriophages (phages) using different
defence systems, such as CRISPR-Cas. Although CRISPR-Cas provides phage resistance …

Comparative Genomics and Evolutionary Analysis of RNA-Binding Proteins of the CsrA Family in the Genus Pseudomonas

PM Sobrero, C Valverde - Frontiers in molecular biosciences, 2020 - frontiersin.org
Gene expression is adjusted according to cellular needs through a combination of
mechanisms acting at different layers of the flow of genetic information. At the …

Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq

MA Matilla, FJ Leeper… - Environmental …, 2015 - Wiley Online Library
Polyketides represent an important class of bioactive natural products with a broad range of
biological activities. We identified recently a large trans‐acyltransferase (AT) polyketide …

The Rsm (Csr) post-transcriptional regulatory pathway coordinately controls multiple CRISPR–Cas immune systems

AR Campa, LM Smith, HG Hampton… - Nucleic acids …, 2021 - academic.oup.com
CRISPR–Cas systems provide bacteria with adaptive immunity against phages and
plasmids; however, pathways regulating their activity are not well defined. We recently …

Non-coding RNAs as antibiotic targets

S Colameco, MA Elliot - Biochemical Pharmacology, 2017 - Elsevier
Antibiotics inhibit a wide range of essential processes in the bacterial cell, including
replication, transcription, translation and cell wall synthesis. In many instances, these …

The LacI–family transcription factor, RbsR, is a pleiotropic regulator of motility, virulence, siderophore and antibiotic production, gas vesicle morphogenesis and …

CM Lee, RE Monson, RM Adams… - Frontiers in …, 2017 - frontiersin.org
Gas vesicles (GVs) are proteinaceous, gas-filled organelles used by some bacteria to
enable upward movement into favorable air/liquid interfaces in aquatic environments …