[HTML][HTML] Deep eutectic solvents as unconventional media for multicomponent reactions

LS Longo Jr, MV Craveiro - Journal of the Brazilian Chemical Society, 2018 - SciELO Brasil
Regarding all the green aspects of sustainable chemical transformations, eco-friendly
processes along with economic development, environmental protection as well as natural …

Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity

C Alonso, M Fuertes, E Martín-Encinas, A Selas… - European Journal of …, 2018 - Elsevier
This work describes the synthesis of 1, 2, 3, 4-tetrahydroquinolinylphosphine oxides,
phosphanes and phosphine sulfides as well as that of quinolinylphosphine oxides and …

Antileishmanial effect of new indeno-1, 5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase

A Tejeria, Y Perez-Pertejo, RM Reguera… - European Journal of …, 2016 - Elsevier
Visceral leishmaniasis is a neglected disease of poor and developing countries. The current
therapeutic approach is based on pentavalent antimonial (Sb V) drugs and amphotericin B …

[PDF][PDF] Anti-cancer and antioxidant activities of some new synthesized 3-secondary amine derivatives bearing imidazo [1, 2-A] pyrimidine

TA Rehan, N Al-Lami, RS Alanee - Eurasian Chemical …, 2021 - researchgate.net
Heterocyclic compounds that contain a bridge of nitrogen atom are of great importance in
medical chemistry and industrial applications as anti-corrosion. Imidazo [1, 2-a] pyrimidines …

Synthesis, crystal structure, and ADME prediction studies of novel imidazopyrimidines as antibacterial and cytotoxic agents

HT Abdel‐Mohsen, A Abood, KJ Flanagan… - Archiv der …, 2020 - Wiley Online Library
In the present study, a novel series of polyfunctionalized imidazopyrimidines 6a–u and 9a–d
were efficiently constructed by a domino reaction between 2‐imino‐6‐substituted‐2, 3 …

Synthesis of symmetrical methylene-bridged imidazoheterocycles using DMSO as methylene source under metal-free conditions

P Liu, Z Shen, Y Yuan, P Sun - Organic & Biomolecular Chemistry, 2016 - pubs.rsc.org
A facile H3PO4-promoted bridging methylenation of imidazopyridines or similar
heterocycles has been described for the synthesis of symmetrical methylene-bridged …

Highly Efficient and Practical Thiocyanation of Imidazopyridines Using an N‐Chlorosuccinimide/NaSCN Combination

H Zhang, Q Wei, S Wei, J Qu… - European Journal of …, 2016 - Wiley Online Library
A direct C–H thiocyanation of imidazo [1, 2‐a] pyridines, and a practical sequential one‐pot
condensation/C–H thiocyanation process, using a combination of N‐chlorosuccinimide …

In (OTf) 3 assisted synthesis of β-carboline C-3 tethered imidazo [1, 2-a] azine derivatives

N Devi, D Singh, G Kaur, S Mor, VPRK Putta… - New Journal of …, 2017 - pubs.rsc.org
Synthesis of β-carboline based natural products and synthetic derivatives is one of the
frontier areas of research owing to their medicinal properties. It is envisaged that 3-formyl-9H …

Synthetic Methodologies of Imidazo [1, 2-a] Pyrimidine: A Review

P Prasher, M Sharma, K Jahan, WN Setzer… - Chemistry Africa, 2024 - Springer
Abstract Imidazo [1, 2-a] pyrimidine, an emerging pharmacophore in medicinal chemistry is
a fused heterocycle containing the biologically potent imidazole and pyrimidine framework …

Mild and Regioselective Three‐component Heteroarylation‐Nitration of Alkenes with Imidazo[1,2‐a]pyridines and tert‐Butyl Nitrite

J Zhang, S Xie, P Liu, P Sun - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
An efficient and regioselective three‐component heteroarylation‐nitration of alkenes with
imidazo [1, 2‐a] pyridines and tert‐butyl nitrite has been developed. The process tolerants a …