Cytosine methylation flags mitochondrial RNA for degradation
E Recazens, AA Jourdain - Trends in Biochemical Sciences, 2024 - cell.com
Mitochondrial double-stranded RNA (dsRNA) can form spontaneously in mitochondria,
blocking mitochondrial gene expression and triggering an immune response. A recent study …
blocking mitochondrial gene expression and triggering an immune response. A recent study …
Mitochondrial RNA methylation in cancer
L Tan, C Zhu, X Zhang, J Fu, T Huang, W Zhang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Mitochondria have a complete and independent genetic system with necessary biological
energy for cancer occurrence and persistence. Mitochondrial RNA (mt-RNA) methylation, as …
energy for cancer occurrence and persistence. Mitochondrial RNA (mt-RNA) methylation, as …
Targeting mitochondrial RNAs enhances the efficacy of the DNA-demethylating agents
Hypomethylating agents (HMAs) such as azacytidine and decitabine are FDA-approved
chemotherapy drugs for hematologic malignancy. By inhibiting DNA methyltransferases …
chemotherapy drugs for hematologic malignancy. By inhibiting DNA methyltransferases …
Recent insights into RNA m5C methylation modification in hepatocellular carcinoma
D Li, Y Liu, G Yang, M He, L Lu - … et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Abstract RNA 5-methylcytosine (m5C) methylation involves the addition of a methyl (-CH3)
group to the cytosine (C) base within an RNA molecule, forming the m5C modification. m5C …
group to the cytosine (C) base within an RNA molecule, forming the m5C modification. m5C …