Multipotent mesenchymal stromal cells (MSCs) represent a rare heterogeneous subset of
pluripotent stromal cells that can be isolated from many different adult tissues that exhibit the …

Exercise training fosters the health and performance of the cardiovascular system, and
represents nowadays a powerful tool for cardiovascular therapy. Exercise exerts its …

Cardiac tissue engineering has been motivated by the need to create functional tissue
equivalents for scientific studies and cardiac tissue repair. We previously demonstrated that …

Myocardial infarcts heal by scarring because myocardium cannot regenerate. To determine
if skeletal myoblasts could establish new contractile tissue, hearts of adult inbred rats were …

Aims It is a dogma of cardiovascular pathophysiology that the increased cardiac mass in
response to increased workload is produced by the hypertrophy of the pre-existing …

Hearing loss is most often the result of hair-cell degeneration due to genetic abnormalities or
ototoxic and traumatic insults. In the postembryonic and adult mammalian auditory sensory …

The reaction of cardiac tissue to acute injury involves interacting cascades of cellular and
molecular responses that encompass inflammation, hormonal signaling, extracellular matrix …

Abnormal heart development is a key feature contributing to the cardiac defects of
congenital heart diseases, which are the most common birth defects in humans, occurring in …

Mitochondria are essential for the development as well as maintenance of the myocardium,
the most energy consuming tissue in the human body. Mitochondria are not only a source of …

One way or another, all species possess the ability to regenerate damaged tissues. The
degree of regeneration, however, varies considerably among tissues within a body and …