The diameter of resistance arteries has a profound effect on the distribution of microvascular
blood flow and the control of systemic blood pressure. Here, we review mechanisms that …

Although an abundant amount of research has been devoted to the study of angiogenesis,
its precise mechanisms are incompletely understood. Numerous clinical trials focused on …

Objective—Although it has been reported that matrix metalloproteinase (MMP)-2 is a major
proteinase in atherosclerotic plaque lesions, there is no direct evidence of the role of MMP-2 …

The role of matrix metalloproteinases (MMPs) in the pathogenesis of abdominal aortic
aneurysm (AAA) has focused on the degradation of the extracellular matrix (ECM). The new …

The nervous and vascular systems contain many common organizational features and
develop similarly in terms of anatomical patterning. During embryogenesis and in regions of …

Age-related macular degeneration (AMD) represents the leading cause of vision loss in the
elderly. Accumulation of lipid-and protein-rich deposits under the retinal pigment epithelium …

The constrained economic context leads laboratories to centralize their routine analyses on
high-throughput platforms, to which blood collection tubes are sent from peripheral sampling …

Matrix metalloproteinases (MMPs) are extracellular matrix–modifying enzymes that are
important in many physiologic and pathologic vascular processes. Dysregulation of MMP …

During early pregnancy, there are marked increases in cardiac output (CO) and global
arterial compliance (AC), as well as decreases in systemic vascular resistance (SVR). We …

Fibulin (fbln)-5 is an elastin-binding protein required for assembly and organization of elastic
fibers. To examine the potential role of fbln-5 in vascular remodeling and neointima …