Post-myocardial infarction fibrosis: Pathophysiology, examination, and intervention

X Yin, X Yin, X Pan, J Zhang, X Fan, J Li… - Frontiers in …, 2023 - frontiersin.org
Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Innovations in the treatment of dystrophic epidermolysis bullosa (DEB): current landscape and prospects

PC Hou, N Del Agua, SM Lwin, CK Hsu… - … and Clinical Risk …, 2023 - Taylor & Francis
Dystrophic epidermolysis bullosa (DEB) is one of the major types of EB, a rare hereditary
group of trauma-induced blistering skin disorders. DEB is caused by inherited pathogenic …

Investigational treatments for epidermolysis bullosa

PC Hou, HT Wang, S Abhee, WT Tu… - American Journal of …, 2021 - Springer
Epidermolysis bullosa (EB) is a heterogeneous group of rare inherited blistering skin
disorders characterized by skin fragility following minor trauma, usually present since birth …

[HTML][HTML] Peptide mediated therapy in fibrosis: Mechanisms, advances and prospects

X Ye, J Li, Z Liu, X Sun, D Wei, L Song, C Wu - Biomedicine & …, 2023 - Elsevier
Fibrosis, a disease characterized by an excess accumulation of extracellular matrix
components, could lead to organ failure and death, and is to blame for up to 45% of all …

Current topics in Epidermolysis bullosa: Pathophysiology and therapeutic challenges

K Natsuga, S Shinkuma, CK Hsu, Y Fujita… - Journal of …, 2021 - Elsevier
Epidermolysis bullosa (EB) is a group of inherited skin and mucosal fragility disorders
resulting from mutations in genes encoding basement membrane zone (BMZ) components …

HMGB1-mediated activation of the inflammatory-reparative response following myocardial infarction

E Foglio, L Pellegrini, MA Russo, F Limana - Cells, 2022 - mdpi.com
Different cell types belonging to the innate and adaptive immune system play mutually non-
exclusive roles during the different phases of the inflammatory-reparative response that …

High-mobility group box 1 fragment ameliorates chronic pancreatitis induced by caerulein in mice

D Hokkoku, K Sasaki, S Kobayashi, T Shimbo… - Journal of …, 2024 - Springer
Background Chronic pancreatitis (CP) is a progressive disease characterized by pancreatic
fibrosis for which effective treatment options are lacking. Mesenchymal stem cells (MSCs) …

Intravenous infusion of bone marrow-derived mesenchymal stem cells improves tissue perfusion in a rat hindlimb ischemia model

S Maeda, T Kawamura, M Sasaki, K Shimamura… - Scientific Reports, 2022 - nature.com
Intravenous infusion of stem cells is a minimally invasive cellular delivery method, though a
few have been reported in a critical limb-threatening ischemia (CLTI) animal model or …

Synthesized HMGB1 peptide prevents the progression of inflammation, steatosis, fibrosis, and tumor occurrence in a non‐alcoholic steatohepatitis mouse model

Y Ishii, A Tsuchiya, K Natsui, Y Koseki… - Hepatology …, 2022 - Wiley Online Library
Aim Non‐alcoholic steatohepatitis (NASH) with fibrosis eventually leads to cirrhosis and
hepatocellular carcinoma. Thus, the development of therapies other than dietary restriction …

Influence of dipeptidyl peptidase-4 (DPP4) on mesenchymal stem-cell (MSC) biology: Implications for regenerative medicine–review

B Torrecillas-Baena, MÁ Gálvez-Moreno… - Stem Cell Reviews and …, 2022 - Springer
Dipeptidyl peptidase IV (DPP4) is a ubiquitous protease that can be found in membrane-
anchored or soluble form. Incretins are one of the main DPP4 substrates. These hormones …