Syndecans are a family of transmembrane heparan sulfate proteoglycans widely expressed
in both developing and adult tissues. Until recently, their role in pathogenesis was largely …

The vertebrate syndecans, which make up a four-member family of small type I
transmembrane heparan sulfate proteoglycans, constitute evolutionarily conserved family …

Heparan sulfate proteoglycans (HSPGs) are critical modulators of growth factor activities.
Skeletal muscle differentiation is strongly inhibited by fibroblast growth factor 2 (FGF-2). We …

The formation of new blood vessels, or angiogenesis, is a necessary process during
development but also for tumour growth and other pathologies. It is promoted by different …

We used a porcine microarray containing 2,880 cDNAs to investigate the response of
macrophages to infection by a virulent African swine fever virus (ASFV) isolate, Malawi …

Objective Syndecan 4, a heparan sulfate proteoglycan, has been associated with
osteoarthritis. The present study was undertaken to analyze the functional role of syndecan …

Extracellular matrix deposition and tissue scarring characterize the process of fibrosis.
Transforming growth factor beta (TGFβ) and Insulin-like growth factor binding protein-3 …

Gliomas are mostly incurable secondary to their diffuse infiltrative nature. Thus, specific
therapeutic targeting of invasive glioma cells is an attractive concept. As cells exit the tumor …

Abstract Decoy receptor 3 (DcR3), a soluble receptor for Fas ligand, LIGHT (homologous to
lymphotoxins shows inducible expression and competes with HSV glycoprotein D for herpes …

Two galactomannans, GALMAN-A and GALMAN-B, were isolated from seeds of Mimosa
scabrella (bracatinga), with deactivation and exposure to native enzymes, respectively. They …