Hippocampus under Pressure: Molecular Mechanisms of Development of Cognitive Impairments in SHR Rats

MY Stepanichev, DI Mamedova, NV Gulyaeva - Biochemistry (Moscow), 2024 - Springer
Data from clinical trials and animal experiments demonstrate relationship between chronic
hypertension and development of cognitive impairments. Here, we review structural and …

Time‐encoded ASL reveals lower cerebral blood flow in the early AD continuum

C Falcon, P Montesinos, L Václavů… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Cerebral blood flow (CBF) is reduced in cognitively impaired (CI)
Alzheimer's disease (AD) patients. We checked the sensitivity of time‐encoded arterial spin …

Vascular Contributions to Healthy Aging and Dementia

Y Ge - Aging and Disease, 2024 - pmc.ncbi.nlm.nih.gov
Vascular pathologies are among the most common contributors to neurodegenerative
changes across the spectrum of normal aging to dementia. Cerebral small vessel disease …

[HTML][HTML] Assessment of cerebral perfusion alterations in dementia with Lewy bodies and Alzheimer's disease

Y Xia, H Jiao, J Han, Y Guo, X Niu… - Quantitative Imaging in …, 2024 - pmc.ncbi.nlm.nih.gov
Background Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are common
forms of dementia, characterized by overlapping clinical symptoms. Functional …

Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study

E Rowsthorn, L Cribb, B Sinclair, W Pham, T Chong… - bioRxiv, 2024 - biorxiv.org
Fluid transport in the neurovascular unit (NVU) is essential for maintaining brain health
through nutrient delivery and waste clearance. NVU integrity and fluid regulation can be …

Frontal, temporal and cerebellar topological property alterations predispose cognitive impairment of ICU sepsis survivors: A resting-state fMRI study

Y Li, J Chen, H Wang, L Wang, J Li, M Li, H Ye, W Liu… - 2024 - researchsquare.com
Background This study aimed to explore the topological alterations of the brain networks of
ICU sepsis survivors and their correlation with cognitive impairment. Methods 16 sepsis …