[HTML][HTML] Mini-review: recent advances in post-translational modification site prediction based on deep learning
Post-translational modifications (PTMs) are closely linked to numerous diseases, playing a
significant role in regulating protein structures, activities, and functions. Therefore, the …
significant role in regulating protein structures, activities, and functions. Therefore, the …
Thirty years of molecular dynamics simulations on posttranslational modifications of proteins
Posttranslational modifications (PTMs) are an integral component to how cells respond to
perturbation. While experimental advances have enabled improved PTM identification …
perturbation. While experimental advances have enabled improved PTM identification …
DeepCap-Kcr: accurate identification and investigation of protein lysine crotonylation sites based on capsule network
Lysine crotonylation (Kcr) is a posttranslational modification widely detected in histone and
nonhistone proteins. It plays a vital role in human disease progression and various cellular …
nonhistone proteins. It plays a vital role in human disease progression and various cellular …
Unlocking the therapeutic potential of drug combinations through synergy prediction using graph transformer networks
Drug combinations are frequently used to treat cancer to reduce side effects and increase
efficacy. The experimental discovery of drug combination synergy is time-consuming and …
efficacy. The experimental discovery of drug combination synergy is time-consuming and …
GPS-Uber: a hybrid-learning framework for prediction of general and E3-specific lysine ubiquitination sites
As an important post-translational modification, lysine ubiquitination participates in
numerous biological processes and is involved in human diseases, whereas the site …
numerous biological processes and is involved in human diseases, whereas the site …
Emerging trends in post-translational modification: Shedding light on Glioblastoma multiforme
Recent multi-omics studies, including proteomics, transcriptomics, genomics, and
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …
i4mC-Deep: an intelligent predictor of N4-methylcytosine sites using a deep learning approach with chemical properties
DNA is subject to epigenetic modification by the molecule N4-methylcytosine (4mC). N4-
methylcytosine plays a crucial role in DNA repair and replication, protects host DNA from …
methylcytosine plays a crucial role in DNA repair and replication, protects host DNA from …
PLP_FS: prediction of lysine phosphoglycerylation sites in protein using support vector machine and fusion of multiple F_Score feature selection
M Sohrawordi, MA Hossain… - Briefings in …, 2022 - academic.oup.com
A newly invented post-translational modification (PTM), phosphoglycerylation, has shown its
essential role in the construction and functional properties of proteins and dangerous human …
essential role in the construction and functional properties of proteins and dangerous human …
NO-HDAC dual inhibitors
N Omidkhah, R Ghodsi - European Journal of Medicinal Chemistry, 2022 - Elsevier
HDAC inhibitors and NO donors have both demonstrated independently broad therapeutic
potential in a variety of diseases. Borretto et al. presented the topic of NO-HDAC dual …
potential in a variety of diseases. Borretto et al. presented the topic of NO-HDAC dual …
Genome-wide identification and expression analysis reveals spinach brassinosteroid-signaling kinase (BSK) gene family functions in temperature stress response
Y Li, H Zhang, Y Zhang, Y Liu, Y Li, H Tian, S Guo… - BMC genomics, 2022 - Springer
Background Brassinosteroid (BR)-signaling kinase (BSK) is a critical family of receptor-like
cytoplasmic kinase for BR signal transduction, which plays important roles in plant …
cytoplasmic kinase for BR signal transduction, which plays important roles in plant …