X-linked hypophosphataemia (XLH) is a rare metabolic bone disorder caused by pathogenic
variants in the PHEX gene, which is predominantly expressed in osteoblasts, osteocytes and …

Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting
from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive …

Objectives Nutritional vitamin D supplements are often used in general pediatrics. Here, the
aim is to address vitamin D supplementation and calcium nutritional intakes in newborns …

Achieving normal growth is one of the most challenging problems in the management of
children with chronic kidney disease (CKD). Treatment with recombinant human growth …

Rickets is a common bone disease worldwide that is associated with disturbances in
calcium and phosphate homeostasis and can lead to short stature and joint deformities …

In children with chronic kidney disease (CKD), optimal control of bone and mineral
homeostasis is essential, not only for the prevention of debilitating skeletal complications …

Infancy and adolescence are crucial periods for bone health, since they are characterized by
intense physical growth and bone development. The unsatisfactory acquisition of bone mass …

Mineral and bone disorders (MBD) are common in patients with chronic kidney disease
(CKD), contributing to significant morbidity and mortality. For several decades, the first-line …

Mineral and bone disorder (MBD) is widely prevalent in children with chronic kidney disease
(CKD) and is associated with significant morbidity. CKD may cause disturbances in bone …

Children with chronic kidney disease (CKD) feature significant challenges to the
maintenance of adequate nutrition and linear growth. Moreover, the impaired nutritional …