The Dioscorea Genus (Yam)—An Appraisal of Nutritional and Therapeutic Potentials

JE Obidiegwu, JB Lyons, CA Chilaka - Foods, 2020 - mdpi.com
The quest for a food secure and safe world has led to continuous effort toward improvements
of global food and health systems. While the developed countries seem to have these …

Advances in the pharmacological activities and mechanisms of diosgenin

C Yan, T You-Mei, YU Su-Lan, HAN Yu-Wei… - Chinese journal of …, 2015 - Elsevier
Diosgenin, a well-known steroid sapogenin derived from plants, has been used as a starting
material for production of steroidal hormones. The present review will summarize published …

Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, IκB kinase activation and NF-κB-regulated gene expression

S Shishodia, BB Aggarwal - Oncogene, 2006 - nature.com
Diosgenin, a steroidal saponin present in fenugreek (Trigonella foenum graecum) and other
plants, has been shown to suppress inflammation, inhibit proliferation, and induce apoptosis …

Bone-targeted extracellular vesicles from mesenchymal stem cells for osteoporosis therapy

Y Wang, J Yao, L Cai, T Liu, X Wang… - International journal …, 2020 - Taylor & Francis
Background: Current drugs used for osteoporosis therapy show strong adverse effects. Stem
cell-derived extracellular vesicles (EVs) provide another choice for osteoporosis therapy …

A review on pharmacological and analytical aspects of diosgenin: a concise report

K Patel, M Gadewar, V Tahilyani, DK Patel - Natural products and …, 2012 - Springer
Diosgenin is a steroidal sapogenin found in plants such as Dioscorea nipponoca, Solanum
incanum, Solanum xanthocarpum and Trigonella foenum graecum. Diosgenin, biologically …

Ceramic drug delivery: a perspective

W Paul, CP Sharma - Journal of biomaterials applications, 2003 - journals.sagepub.com
Different ceramic substances are offered in the market as bone substitute materials. These
include monophasic calcium phosphate ceramics of tricalciumphosphate (TCP) or …

[HTML][HTML] Study of Foeniculum vulgare effect on folliculogenesis in female mice

M Khazaei, A Montaseri, MR Khazaei… - … journal of fertility & …, 2011 - ncbi.nlm.nih.gov
Background: Foeniculum vulgare (FVE) is used in traditional medicine for its antiseptic,
palliative and anti-inflammatory effects. Traditionally, FVE is utilized for treating female …

Estrogenic effect of yam ingestion in healthy postmenopausal women

WH Wu, LY Liu, CJ Chung, HJ Jou… - Journal of the American …, 2005 - Taylor & Francis
Objective: Yam (Dioscorea) has been used to treat menopausal symptom folklorically. This
study was to investigate the effects of yam ingestion on lipids, antioxidant status, and sex …

[PDF][PDF] The impact of cooking on the proximate composition and anti-nutritional factors of water yam (Dioscorea alata)

VC Ezeocha, PC Ojimelukwe - Journal of Stored Products and Postharvest …, 2012 - Citeseer
Raw and boiled water yam tubers (Dioscorea alata) were analyzed for proximate contents
such as ash, crude protein, carbohydrate, crude fibre, crude lipid, energy and anti-nutrients …

Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen …

ML Yen, JL Su, CL Chien, KW Tseng, CY Yang… - Molecular …, 2005 - ASPET
Diosgenin, extracted from the root of wild yam (Dioscorea villosa), has been reported to
demonstrate an opportunity for medical application. Vascular endothelial growth factor-A …