Tumor metastasis is the major cause of mortality from cancer. Metabolic rewiring and the
metastatic cascade are highly intertwined, co-operating to promote multiple steps of cancer …

Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved
proteins in living organisms. AHCY catalyzes the reversible break of S …

Background Epigenetic alterations are involved in various aspects of colorectal
carcinogenesis. N 6-methyladenosine (m 6 A) modifications of RNAs are emerging as a new …

Background The macrophage, one of the several key immune cell types, is believed to be
involved in tumorigenesis. However, the mechanism of macrophages promoting tumor …

Background Inflammation, a vital immune response to infection and injury, is mediated by
macrophage activation. While spleen tyrosine kinase (Syk) and myeloid differentiation …

Solamargine is a steroidal alkaloid glycoside isolated from Solanum nigrum. The aim of this
study was to investigate the effects of solamargine on tumor migration and invasion in …

Abstract Ethnopharmacological relevance Artemisia asiatica Nakai (Compositae) is a
representative herbal plant used to treat infection and inflammatory diseases. Although …

Highlights•This review mainly summarizes the anti-cancer effects of adenosine analogues in
market and clinical trials.•This review describes the anti-cancer strategies and mechanisms …

Our previous big data analyses showed a high level of association between chitinase 3 like1
(CHI3L1) expression and lung tumor development. In the present study, we investigated …

Recently, functional connections between S-adenosylhomocysteine hydrolase (AHCY)
activity and cancer have been reported. As the properties of AHCY include the hydrolysis of …