A number of studies have provided evidence for a link between thyroid hormones and
physiological or pathophysiological conditions associated with reproduction. Most of the …

Estrogens work by binding to and activating specific estrogen receptors (ERs). Although
mammals have two major nuclear ER subtypes (ERα and ERβ), three subtypes have been …

In the last years the concern about the negative effects of phthalates on reproduction
significantly increased. Considering that, at date data available dealing with the adverse …

The nuclear receptors encompass a group of regulatory proteins involved in a number of
physiological processes. The estrogen receptors (ERs), of which one alpha and one beta …

Genetically distinct estrogen receptor (ER) subtypes (ERα and ERβ) play a major role in
mediating estrogen actions in vertebrates, but their unique and overlapping functions are not …

In the present study, we have investigated the endocrine disruptive effects of waterborne di-
(2-ethylhexyl) phthalate (DEHP: 0 (control), 10, 100, 200 and 400 μg/L) on juvenile Clarias …

Solid waste dumpsites (SWDs) and landfills are significant sources of emerging
contaminants to terrestrial and aquatic ecosystems. We have studied the endocrine …

In the present study, existing regulatory frameworks and test systems for assessing potential
endocrine active chemicals are described, and associated challenges are discussed, along …

Background Aquatic organisms are continuously exposed to complex mixtures of chemicals,
many of which can interfere with their endocrine system, resulting in impaired reproduction …

Background Oocyte maturation in fish involves numerous cell signaling cascades that are
activated or inhibited during specific stages of oocyte development. The objectives of this …