Glutathione (GSH) is the most abundant non-protein thiol present at millimolar
concentrations in mammalian tissues. As an important intracellular antioxidant, it acts as a …

Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …

Nanomedicines are attractive paradigms to deliver drugs, contrast agents,
immunomodulators, and gene editors for cancer therapy and diagnosis. However, the …

In the last few decades, several natural bioactive agents have been widely utilized in the
treatment and prevention of many diseases owing to their unique and versatile therapeutic …

Cerium oxide nanoparticles (CeNPs) exhibit antioxidant properties both in vitro and in vivo.
This is due to the self-regeneration of their surface, which is based on redox-cycling …

Due to their good absorption, satisfactory biocompatibility, and high safety, hydrogels have
been widely used in the field of biomedicine, including for drug delivery and tissue …

Glucose oxidase (GOx) can react with intracellular glucose and oxygen (O2) to produce
hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of …

Abstract Glutathione peroxidase 4 (GPX4) has been confirmed to inhibit ferroptosis in cancer
cells, however, whether GPX4 serves as an oncogene is not clear. In this study, the …

Until now, enormous smart materials have been engineered with endogenous stimulators
such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …