[HTML][HTML] 68Ga-DOTA and analogs: Current status and future perspectives

K Kilian - Reports of Practical Oncology & Radiotherapy, 2014 - Elsevier
The construction of the 68 Ge/68 Ga generator has increased application of
radiopharmaceuticals labeled with this isotope in medicine. 68 Ga-PET is widely employed …

[HTML][HTML] Benzamide derivative radiotracers targeting melanin for melanoma imaging and therapy: Preclinical/clinical development and combination with other …

J Rouanet, M Quintana, P Auzeloux, F Cachin… - Pharmacology & …, 2021 - Elsevier
Cutaneous melanoma arises from proliferating melanocytes, cells specialized in the
production of melanin. This property means melanin can be considered as a target for …

Preclinical evaluation of melanocortin-1 receptor (MC1-R) specific 68Ga-and 44Sc-labeled DOTA-NAPamide in melanoma imaging

G Nagy, N Dénes, A Kis, JP Szabó, E Berényi… - European Journal of …, 2017 - Elsevier
Purpose Alpha melanocyte stimulating hormone (α-MSH) enhances melanogenesis in
melanoma malignum by binding to melanocortin-1 receptors (MC1-R). Earlier studies …

Melanin-targeting radiotracers and their preclinical, translational, and clinical status: from past to future

X Zhang, Z Lin, Y Feng, F Kang, J Wang… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Melanin is one of the representative biomarkers of malignant melanoma and a potential
target for diagnosis and therapy. With advancements in chemistry and radiolabeling …

68Ga-labeled amphiphilic polymer nanoparticles for PET imaging of sentinel lymph node metastasis

Q Chen, X Fu, H Cai, S Fu, Z Cai, M Li… - Regenerative …, 2023 - academic.oup.com
Precise diagnosis of lymph node metastasis is important for therapeutic regimen planning,
prognosis analysis and probably better outcomes for cancer patients. In this work, 68Ga …

Synthesis and evaluation of 18F-labeled procainamide as a PET imaging agent for malignant melanoma

A Pyo, M Yun, B Song, SY Kwon, JJ Min… - Bioorganic & Medicinal …, 2023 - Elsevier
Malignant melanoma has an aggressive nature and a high metastatic propensity resulting in
the highest mortality rate of any skin cancer. In this study, we synthesized 18 F-labeled …

61Cu-Labelled radiodiagnostics of melanoma with NAPamide-targeted radiopharmaceutical

I Kálmán-Szabó, S Bunda, N Lihi, Z Szaniszló… - International Journal of …, 2023 - Elsevier
Malignant melanoma is a major public health problem with an increasing incidence and
mortality in the Caucasian population due to its significant metastatic potential. The early …

Ultrasensitive detection of malignant melanoma using PET molecular imaging probes

A Pyo, DY Kim, H Kim, D Lim… - Proceedings of the …, 2020 - National Acad Sciences
Malignant melanoma has one of the highest mortality rates of any cancer because of its
aggressive nature and high metastatic potential. Clinical staging of the disease at the time of …

Radioisotope Co-57 incorporated layered double hydroxide nanoparticles as a cancer imaging agent

TH Kim, JY Lee, MK Kim, JH Park, JM Oh - RSC advances, 2016 - pubs.rsc.org
Radioisotope Co-57 was stably incorporated into a framework of layered double hydroxide
nanoparticles through isomorphous substitution. An in vitro cellular uptake test resulted in∼ …

Comparative preclinical evaluation of 68Ga-NODAGA and 68Ga-HBED-CC conjugated procainamide in melanoma imaging

G Trencsényi, N Dénes, G Nagy, A Kis, A Vida… - … of pharmaceutical and …, 2017 - Elsevier
Malignant melanoma is the most aggressive form of skin cancer. The early detection of
primary melanoma tumors and metastases using non-invasive PET imaging determines the …