Amygdala pain mechanisms
V Neugebauer - Pain control, 2015 - Springer
A limbic brain area, the amygdala plays a key role in emotional responses and affective
states and disorders such as learned fear, anxiety, and depression. The amygdala has also …
states and disorders such as learned fear, anxiety, and depression. The amygdala has also …
The effect of pain on cognitive function: a review of clinical and preclinical research
O Moriarty, BE McGuire, DP Finn - Progress in neurobiology, 2011 - Elsevier
Cognitive impairment is commonly associated with the pain experience. This impairment
represents a major obstacle to daily activities and rehabilitation, especially in the chronic …
represents a major obstacle to daily activities and rehabilitation, especially in the chronic …
Dual and opposing functions of the central amygdala in the modulation of pain
TD Wilson, S Valdivia, A Khan, HS Ahn, AP Adke… - Cell reports, 2019 - cell.com
Pain perception is essential for survival and can be amplified or suppressed by
expectations, experiences, and context. The neural mechanisms underlying bidirectional …
expectations, experiences, and context. The neural mechanisms underlying bidirectional …
Neuropathic pain: a maladaptive response of the nervous system to damage
M Costigan, J Scholz, CJ Woolf - Annual review of neuroscience, 2009 - annualreviews.org
Neuropathic pain is triggered by lesions to the somatosensory nervous system that alter its
structure and function so that pain occurs spontaneously and responses to noxious and …
structure and function so that pain occurs spontaneously and responses to noxious and …
Clinical features and pathophysiology of complex regional pain syndrome
A complex regional pain syndrome (CRPS)—multiple system dysfunction, severe and often
chronic pain, and disability—can be triggered by a minor injury, a fact that has fascinated …
chronic pain, and disability—can be triggered by a minor injury, a fact that has fascinated …
Left and right hemispheric lateralization of the amygdala in pain
Hemispheric asymmetries within the brain have been identified across taxa and have been
extensively studied since the early 19th century. Here, we discuss lateralization of a brain …
extensively studied since the early 19th century. Here, we discuss lateralization of a brain …
MAP kinase and pain
Mitogen-activated protein kinases (MAPKs) are important for intracellular signal transduction
and play critical roles in regulating neural plasticity and inflammatory responses. The MAPK …
and play critical roles in regulating neural plasticity and inflammatory responses. The MAPK …
Amygdala plasticity and pain
JM Thompson, V Neugebauer - Pain Research and …, 2017 - Wiley Online Library
The amygdala is a limbic brain region that plays a key role in emotional processing,
neuropsychiatric disorders, and the emotional‐affective dimension of pain. Preclinical and …
neuropsychiatric disorders, and the emotional‐affective dimension of pain. Preclinical and …
Alcohol dependence as a chronic pain disorder
Dysregulation of pain neurocircuitry and neurochemistry has been increasingly recognized
as playing a critical role in a diverse spectrum of diseases including migraine, fibromyalgia …
as playing a critical role in a diverse spectrum of diseases including migraine, fibromyalgia …
The amygdala between sensation and affect: a role in pain
The amygdala is a structure of the temporal lobe thought to be involved in assigning
emotional significance to environmental information and triggering adapted physiological …
emotional significance to environmental information and triggering adapted physiological …