Sepsis is a clinical syndrome that results from a systemic response of the host to an
infection. Activation of inflammatory pathways, including the cytokine network, is considered …

Sepsis and systemic inflammatory response syndrome (SIRS) are associated with an
exacerbated production of both pro-and anti-inflammatory mediators that are mainly …

Background In 1997, the first documented instance of human respiratory disease and death
associated with a purely avian H5N1 influenza virus resulted in an overall case-fatality rate …

Induction of pneumonia in C57Bl/6 mice by intranasal inoculation with 106 cfu of
Streptococcus pneumoniae resulted in sustained expression of interleukin (IL)-6 mRNA in …

Objective. Serum procalcitonin (PCT), C-reactive protein (CRP) and interleukin-6 (IL-6)
concentrations were measured in 126 children hospitalized for community-acquired …

Sodium absorption by an amiloride-sensitive channel is the main driving force of lung liquid
clearance at birth and lung edema clearance in adulthood. In this study, we tested whether …

BACKGROUND The inflammatory response has been widely investigated in patients with
acute respiratory distress syndrome (ARDS) and pneumonia. Studies investigating the …

There is a need for more insight into the pathogenesis of Streptococcus pneumoniae
pneumonia, as the fatality rate associated with this disease remains high despite …

Introduction Early use of corticosteroids in patients affected by pandemic (H1N1) v influenza
A infection, although relatively common, remains controversial. Methods Prospective …

Objectives: To review the involvement of coagulation and fibrinolysis in the pathogenesis of
acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), pulmonary infection, and …