Global Cancer Statistics 2022: the trends projection analysis
BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …
year. The disease variations in different parts of the world, the impact of available medical …
Long-acting HIV pre-exposure prophylaxis (PrEP) approaches: recent advances, emerging technologies, and development challenges
V Agrahari, SM Anderson, MM Peet… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Poor or inconsistent adherence to daily oral pre-exposure prophylaxis (PrEP)
has emerged as a key barrier to effective HIV prevention. The advent of potent long-acting …
has emerged as a key barrier to effective HIV prevention. The advent of potent long-acting …
Corona virus SARS-CoV-2 disease COVID-19: Infection, prevention and clinical advances of the prospective chemical drug therapeutics
The recent outbreak of Corona virus SARS-CoV-2 disease COVID-19 in the China and
subsequent intermittent spread of infection to other countries has alarmed the medical and …
subsequent intermittent spread of infection to other countries has alarmed the medical and …
[HTML][HTML] Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles
Long-acting parenteral (LAP) antiretroviral drugs have generated considerable interest for
treatment and prevention of HIV-1 infection. One new LAP is cabotegravir (CAB), a highly …
treatment and prevention of HIV-1 infection. One new LAP is cabotegravir (CAB), a highly …
Comparative antiviral activity of remdesivir and anti-HIV nucleoside analogs against human coronavirus 229E (HCoV-229E)
Remdesivir is a nucleotide prodrug that is currently undergoing extensive clinical trials for
the treatment of COVID-19. The prodrug is metabolized to its active triphosphate form and …
the treatment of COVID-19. The prodrug is metabolized to its active triphosphate form and …
Viral infection mitigations using advanced nanomaterials and tools: lessons from SARS-CoV-2 for future prospective interventions
BS Chhikara, R Kumar, P Bazard… - Journal of Materials …, 2021 - pubs.iscience.in
The emergence of recent corona virus SARS-CoV-2-led pandemic infection has generated
the incessant demand for the evaluation and development of suitable advanced materials …
the incessant demand for the evaluation and development of suitable advanced materials …
Amphiphilic cell-penetrating peptides containing natural and unnatural amino acids as drug delivery agents
A series of cyclic peptides,[(DipR)(WR) 4],[(DipR) 2 (WR) 3],[(DipR) 3 (WR) 2],[(DipR) 4
(WR)], and [DipR] 5, and their linear counterparts containing arginine (R) as positively …
(WR)], and [DipR] 5, and their linear counterparts containing arginine (R) as positively …
Synthesis and Antiviral Activity of Novel β-D-N4-Hydroxycytidine Ester Prodrugs as Potential Compounds for the Treatment of SARS-CoV-2 and Other Human …
ES Darnotuk, AE Siniavin, NS Shastina, SI Luyksaar… - Pharmaceuticals, 2023 - mdpi.com
The spread of COVID-19 infection continues due to the emergence of multiple transmissible
and immune-evasive variants of the SARS-CoV-2 virus. Although various vaccines have …
and immune-evasive variants of the SARS-CoV-2 virus. Although various vaccines have …
Creation of a long-acting nanoformulated 2′, 3′-dideoxy-3′-thiacytidine
Background: Antiretroviral drug discovery and formulation design will facilitate viral
clearance in infectious reservoirs. Although progress has been realized for selected …
clearance in infectious reservoirs. Although progress has been realized for selected …
Cyclic peptide-capped gold nanoparticles as drug delivery systems
A number of cyclic peptides were synthesized and evaluated as simultaneous reducing and
capping agents for generation of cyclic peptide-capped gold nanoparticles (CP-AuNPs) …
capping agents for generation of cyclic peptide-capped gold nanoparticles (CP-AuNPs) …