The vascular smooth muscle cell (SMC) in mature animals is a highly specialized cell whose
principal function is contraction. The fully differentiated or mature SMC proliferates at an …

Phenotypic modulation of smooth muscle cells (SMCs) plays an integral role in
atherosclerosis, hypertension and leiomyogenic tumorigenicity. The morphological …

It is generally accepted that the de-differentiation of smooth muscle cells, from the contractile
to the proliferative/synthetic phenotype, has an important role during vascular remodelling …

Sustained delivery of heparin to the localized adventitial surface of grafted blood vessels
has been shown to prevent the vascular smooth muscle cell (VSMC) proliferation that can …

Transforming growth factor-β (TGF-β)–induced α-smooth muscle actin (ASMA) expression is
a key indicator of myofibroblast differentiation from fibroblasts. Recent studies suggest that a …

Background In the present series of experiments, we examined the onset of cell proliferation
and growth factor expression after balloon overstretch injury to porcine coronary arteries …

We undertook a detailed cellular and ultrastructural examination of bronchial biopsies from
seven allergic asthmatic patients and 10 nonasthmatic control subjects (five atopic and five …

The characterization of a novel 59-kD cytoskeletal protein is described. It is exclusively
observed in smooth muscle cells by Northern blotting and immunohistochemical analysis …

Smooth muscle cells (SMC) exhibit a functional plasticity, modulating from the mature
phenotype in which the primary function is contraction, to a less differentiated state with …

Densitometry data generated for Western blots are commonly used to compare protein
abundance between samples. In the last decade, it has become apparent that assumptions …