[HTML][HTML] The immune microenvironment in cartilage injury and repair

M Li, H Yin, Z Yan, H Li, J Wu, Y Wang, F Wei, G Tian… - Acta Biomaterialia, 2022 - Elsevier
The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

[HTML][HTML] Advanced hydrogels for the repair of cartilage defects and regeneration

W Wei, Y Ma, X Yao, W Zhou, X Wang, C Li, J Lin… - Bioactive materials, 2021 - Elsevier
Cartilage defects are one of the most common symptoms of osteoarthritis (OA), a
degenerative disease that affects millions of people world-wide and places a significant …

Surgical and tissue engineering strategies for articular cartilage and meniscus repair

H Kwon, WE Brown, CA Lee, D Wang… - Nature Reviews …, 2019 - nature.com
Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately
results in arthritis. Different forms of arthritis affect~ 50 million people in the USA alone, and it …

Repair and tissue engineering techniques for articular cartilage

EA Makris, AH Gomoll, KN Malizos, JC Hu… - Nature Reviews …, 2015 - nature.com
Chondral and osteochondral lesions due to injury or other pathology commonly result in the
development of osteoarthritis, eventually leading to progressive total joint destruction …

Cell-based tissue engineering strategies used in the clinical repair of articular cartilage

BJ Huang, JC Hu, KA Athanasiou - Biomaterials, 2016 - Elsevier
One of the most important issues facing cartilage tissue engineering is the inability to move
technologies into the clinic. Despite the multitude of current research in the field, it is known …

Design, clinical translation and immunological response of biomaterials in regenerative medicine

K Sadtler, A Singh, MT Wolf, X Wang… - Nature Reviews …, 2016 - nature.com
The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …

Autologous chondrocyte implantation in the knee: systematic review and economic evaluation

H Mistry, M Connock, J Pink… - Health Technology …, 2017 - wrap.warwick.ac.uk
Background: The surfaces of the bones in the knee are covered with articular cartilage, a
rubber-like substance that is very smooth, allowing frictionless movement in the joint and …

Collagen scaffolds in cartilage tissue engineering and relevant approaches for future development

V Irawan, TC Sung, A Higuchi, T Ikoma - Tissue engineering and …, 2018 - Springer
Background: Cartilage tissue engineering (CTE) aims to obtain a structure mimicking native
cartilage tissue through the combination of relevant cells, three-dimensional scaffolds, and …

Highlights on advancing frontiers in tissue engineering

N Ashammakhi, A GhavamiNejad, R Tutar… - … Engineering Part B …, 2022 - liebertpub.com
The field of tissue engineering continues to advance, sometimes in exponential leaps
forward, but also sometimes at a rate that does not fulfill the promise that the field imagined a …

Clinical application status of articular cartilage regeneration techniques: tissue‐engineered cartilage brings new hope

S Jiang, W Guo, G Tian, X Luo, L Peng… - Stem Cells …, 2020 - Wiley Online Library
Hyaline articular cartilage lacks blood vessels, lymphatics, and nerves and is characterised
by limited self‐repair ability following injury. Traditional techniques of articular cartilage …