Plants are a rich source of bioactive compounds, many of which have been exploited for
cosmetic, nutritional, and medicinal purposes. Through the characterization of metabolic …

Medicinal plants produce a diverse group of phytocompounds like anthraquinones,
alkaloids, anthocyanins, flavonoids, saponins, and terpenes which are used in …

In the last years, hairy root (HR) cultures are gaining attention in the biotechnology industry.
This particular plant cell culture derives from explants infected with Agrobacterium …

Hyoscyamine and scopolamine, belonging to medicinal tropane alkaloids (MTAs), are
potent anticholinergic drugs. Their industrial production relies on medicinal plants, but the …

Nature's own genetic engineer Agrobacterium rhizogenes was discovered more than 40
years ago, and an increasing number of publications on the use of hairy roots in …

(−)-Hyoscyamine, the enantiomerically pure form of atropine, and its derivative scopolamine
are tropane alkaloids that are extensively used in medicine. Hyoscyamine 6β-hydroxylase …

Abstract The (-)-hyoscyamine, atropine and scopolamine (hyoscine) are three valuable
tropane alkaloids while scopolamine is the most important member of this group for the …

The overexploitation of medicinal plants is depleting gene pool at an alarming rate. In this
scenario inducing the genetic variability through targeted mutations could be beneficial in …

Main conclusion Microscopic techniques remain an integral tool which has allowed for the
better understanding and manipulation of in vitro plant culture systems. The recent …

Tropane alkaloids (TAs) are plant-derived natural products that have been exploited
throughout history for their pharmaceutical properties. TAs are characterised by the …